Enhancing biomedical search interfaces with images.

Bioinform Adv

Department of Computer Science, University of Illinois Chicago, Chicago, IL 60607, USA.

Published: July 2023

Motivation: Figures in biomedical papers communicate essential information with the potential to identify relevant documents in biomedical and clinical settings. However, academic search interfaces mainly search over text fields.

Results: We describe a search system for biomedical documents that leverages image modalities and an existing index server. We integrate a problem-specific taxonomy of image modalities and image-based data into a custom search system. Our solution features a front-end interface to enhance classical document search results with image-related data, including page thumbnails, figures, captions and image-modality information. We demonstrate the system on a subset of the CORD-19 document collection. A quantitative evaluation demonstrates higher precision and recall for biomedical document retrieval. A qualitative evaluation with domain experts further highlights our solution's benefits to biomedical search.

Availability And Implementation: A demonstration is available at https://runachay.evl.uic.edu/scholar. Our code and image models can be accessed via github.com/uic-evl/bio-search. The dataset is continuously expanded.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359625PMC
http://dx.doi.org/10.1093/bioadv/vbad095DOI Listing

Publication Analysis

Top Keywords

search interfaces
8
search system
8
image modalities
8
search
6
biomedical
5
enhancing biomedical
4
biomedical search
4
interfaces images
4
images motivation
4
motivation figures
4

Similar Publications

Antimicrobial resistance (AMR) is a major cause of death worldwide. This urges the search for alternatives to antibiotics, and antimicrobial polymers hold promise due to their reduced susceptibility to AMR. The topology of such macromolecules has a strong impact on their activity, with bottlebrush architectures outperforming their linear counterparts significantly.

View Article and Find Full Text PDF

THE EFFECTIVENESS OF PLATELET RICH FIBRIN IN ALVEOLAR RIDGE RECONSTRUCTIVE OR GUIDED BONE REGENERATIVE PROCEDURES: A SYSTEMATIC REVIEW AND META-ANALYSIS.: platelet rich fibrin in alveolar ridge augmentation.

J Dent

December 2024

Periodontology Unit, Centre for Host Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, United Kingdom. Electronic address:

Introduction And Objectives: Clinical studies have shown favorable outcomes following use of platelet rich fibrin (PRF), either alone or in conjunction with biomaterials for alveolar ridge reconstruction (ARR) or guided bone regeneration (GBR) . While PRF application accelerates wound healing and reduces postoperative discomfort, its effects on the alveolar bone gain, as part of ARR or GBR is less clear. Therefore, this study aims to investigate the clinical effectiveness of PRF when used in ARR or GBR, as well as postoperative discomfort following these procedures.

View Article and Find Full Text PDF

Children use nasogastric tubes (NGTs) to ensure optimum nutrition and medication delivery when oral feeding fails or when they experience faltering growth. Although this method is less invasive, children may experience complications associated with NGTs. There is a gap in the literature regarding the types and prevention of complications of NGTs in the pediatric population at home.

View Article and Find Full Text PDF

Exploring the druggability of the UEV domain of human TSG101 in search for broad-spectrum antivirals.

Protein Sci

January 2025

Department of Physical Chemistry, Institute of Biotechnology, and Unit of Excellence in Chemistry Applied to Biomedicine and Environment, School of Sciences, University of Granada, Granada, Spain.

The ubiquitin E2 variant domain of TSG101 (TSG101-UEV) plays a pivotal role in protein sorting and virus budding by recognizing PTAP motifs within ubiquitinated proteins. Disruption of TSG101-UEV/PTAP interactions has emerged as a promising strategy for the development of host-oriented broad-spectrum antivirals with low susceptibility to resistance. TSG101 is a challenging target characterized by an extended and flat binding interface, low affinity for PTAP ligands, and complex binding energetics.

View Article and Find Full Text PDF

Intrinsically disordered proteins (IDPs) make up around 30% of eukaryotic proteomes and play a crucial role in cellular processes and in pathological conditions such as neurodegenerative disorders and cancers. However, IDPs exhibit dynamic conformational ensembles and are often involved in the formation of biomolecular condensates. Understanding the function of IDPs is critical to research in many areas of science.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!