This case report presents an interesting and rare cause of meningitis in young infants, . Not only is the organism unusual but the well appearance of the infant made this diagnosis surprising. The 2021 American Academy of Pediatrics (AAP) clinical practice guidelines on well-appearing febrile infants brought a national guideline on the evaluation and management of fever in infants. However, providers should be aware that there is room for shared decision-making and that the guideline will miss a very small percentage of well-appearing infants with invasive bacterial infections.
A world free of dog-mediated human rabies by 2030 would be an outstanding achievement. This ambitious goal for a neglected tropical disease, set by the World Organisation for Animal Health (WOAH), the World Health Organization, the Food and Agriculture Organization of the United Nations and the Global Alliance for Rabies Control together with partners and countries, has a clear and achievable pathway to success. In the 100 years since the inception of WOAH, many scientific tools have been developed to support the elimination of dog-mediated rabies.
OrtopediaVet Veterinary Clinic, Dr. Eloy Curuci and team. Volta Redonda Street, 670 - Campo Belo, São Paulo, State of São Paulo, Brazil, Zip code 04608-011.
Objectives: There is a lack of literature regarding the surgical management of high-grade patellar luxation in cats. Among the available options, corrective osteotomies are suitable for correcting severe bone deformities. Therefore, this study aimed to report on the surgical management of grade IV medial patellar luxation (MPL) through tibial corrective osteotomies in two cats.
This case describes a previously unreported complication of maxillary canine root canal therapy in a cat. A 5-year-old Russian Blue cat was presented with a complicated crown fracture (pulp exposure) of its left maxillary canine tooth (204). To salvage the tooth, root canal therapy was initiated but not completed due to hemorrhage within the canal.
The PD-1/PDL-1 immune checkpoint inhibitors revolutionized cancer treatment, yet osteosarcoma remains a therapeutic challenge. In some types of cancer, PD-1 receptor is not solely expressed by immune cells but also by cancer cells, acting either as a tumor suppressor or promoter. While well-characterized in immune cells, little is known about the role and interactome of the PD-1 pathway in cancer.
Wound healing is a complex biological process critical for maintaining an organism's structural integrity and tissue repair following an infection or injury. Recent studies have unveiled the mechanisms involving the coordination of biochemical and mechanical responses in the tissue in wound healing. In this article, we focus on the healing property of an epithelial tissue as a material while the effects of biological mechanisms such as cell proliferation, tissue intercalation, cellular migration, cell crawling, and filopodia protrusion is minimal.
