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Effect of Optimal Heart Rate on Left Ventricular Remodeling in Patients with Systolic Heart Failure Following Acute Coronary Syndrome.
Int Heart J
September 2024
Second Department of Internal Medicine, University of Toyama.
The optimal therapeutic approach to facilitate reverse remodeling is desired in patients with systolic heart failure following acute coronary syndrome (ACS). The association between heart rate (HR) and reverse remodeling in this cohort has remained elusive.Patients with left ventricular ejection fraction (LVEF) < 50% who received echocardiography assessments following ACS were retrospectively included.
View Article and Find Full Text PDFIvabradine Alleviates Experimental Autoimmune Myocarditis-Mediated Myocardial Injury.
Int Heart J
February 2024
Department of Cardiology, Fourth Affiliated Hospital, Harbin Medical University.
Ivabradine (IVA) reduces heart rate by inhibiting hyperpolarization-activated cyclic nucleotide-gated channels (HCNs), which play a role in the promotion of pacemaker activity in cardiac sinoatrial node cells. HCNs are highly expressed in neural and myocardial tissues and are involved in the modulation of inflammatory neuropathic pain. However, whether IVA exerts any effect on myocardial inflammation in the pathogenesis of heart failure is unclear.
View Article and Find Full Text PDFCardiac tamponade and basilar artery aneurysm following leptospirosis: A case report.
Int J Crit Illn Inj Sci
December 2023
Faculty of Medical Sciences, King George's Medical University, Lucknow, Uttar Pradesh, India.
Complications involving the heart are rare in leptospirosis, and cardiac tamponade is still rarer. We report the case of a 42-year-old hypertensive woman who presented with complaints of cough for 2 months and breathlessness for 1 month. One month later, she developed shortness of breath and loss of consciousness.
View Article and Find Full Text PDFEffectiveness and safety of ivabradine in Chinese patients with chronic heart failure: an observational study.
ESC Heart Fail
April 2024
Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
Aims: A therapeutic strategy for chronic heart failure (HF) is to lower resting heart rate (HR). Ivabradine is a well-known HR-lowering agent, but limited prospective data exist regarding its use in Chinese patients. This study aimed to evaluate the effectiveness and safety of ivabradine in Chinese patients with chronic HF.
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