New bisabolane-type sesquiterpenoid from BTBU20213012.

Nat Prod Res

Key Laboratory of Geriatric Nutrition and Health, Ministry of Education of China; School of Light Industry, Beijing Technology and Business University, Beijing, P. R. China.

Published: August 2024

A new bisabolane-type sesquiterpenoid, named (+)-8-dehydroxylaustrosene (), along with ten known compounds, penicibisabolanes E () and G (), (+)-austrosene (), ()-(+)-11-dehydrosydonic acid (), sydonic acid (), (7,11)-(+)-12-hydroxysydonic acid (), (-)-()-hydroxysydonic acid (), pseudaboydin A (), (-)-(7 ,10)--10-hydroxysydowic acid (), lumichrome (), were identified from the fungus BTBU20213012 isolated from a marine sediment sample from the Western Pacific. The structures of the compounds were identified by HRESIMS and NMR data analysis. Compound showed weak antimicrobial activity against with MIC value of 200 μg/mL.

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http://dx.doi.org/10.1080/14786419.2023.2236764DOI Listing

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