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Cholecystectomy-induced thrombotic microangiopathy (TMA) in a postpartum patient successfully treated with eculizumab: a case report.
J Med Case Rep
December 2024
Department of Internal Medicine, University of California Irvine Medical Center, 333 City Blvd West, Suite 500, Orange, CA, 92868, USA.
Background: Thrombotic microangiopathy (TMA) is a rare, life-threatening disorder characterized by microangiopathic hemolytic anemia, thrombocytopenia, and end-organ damage. Atypical hemolytic uremic syndrome (aHUS) is even less common, comprising less than 10% of hemolytic uremic syndrome (HUS) cases. aHUS in postpartum is associated with poor maternal outcomes, with the majority of cases resulting in end-stage renal disease.
View Article and Find Full Text PDFComplement-mediated hemolytic uremic syndrome associated with postpartum hemorrhage: case series and systematic review of individual participant data.
Res Pract Thromb Haemost
November 2024
Faculty of Medicine, Tel Aviv University, Ramat-Aviv, Israel.
Background: Postpartum hemorrhage is considered a risk factor for pregnancy-associated complement-mediated hemolytic uremic syndrome (CM-HUS; previously known as atypical hemolytic uremic syndrome) but has not been systematically studied.
Objectives: To systematically examine the role of postpartum hemorrhage in precipitating CM-HUS and to describe the characteristics of postpartum hemorrhage-associated CM-HUS, its prognosis and recommended management.
Methods: A systematic review of individual participant data from case series and reports in addition to a case series from our institution.
Charcot-Marie-Tooth Disease Presenting in the Postpartum Period: A Case Report.
Cureus
December 2024
Clinical Neurophysiology, University Hospital of Wales, Cardiff, GBR.
Charcot-Marie-Tooth disease (CMT) is the most common hereditary peripheral neuropathy. It presents a wide range of genetic and phenotypic heterogeneity. CMT disease type 1A (CMT1A), caused by PMP22 gene duplication, represents the most common subtype of CMT in Western countries.
View Article and Find Full Text PDFVariability in perinatal sleep quality is associated with an atypical cortisol awakening response and increased mood symptoms.
Psychoneuroendocrinology
November 2024
University of Colorado, Colorado Springs, USA.
Objective: Pregnancy is often typified with a decrease in sleep quality, which for many women, progressively worsens across gestation and into the postpartum. A mechanism linking poor sleep with certain adverse pregnancy outcomes is dysregulation of the HPA axis resulting in atypically elevated cortisol production. While total cortisol output normally increases across pregnancy, the cortisol awakening response (CAR), a response to waking up, is influenced by factors such as stress and mood.
View Article and Find Full Text PDFRates of Major Depressive Disorder and Bipolar Disorder in Black and White Postpartum Women.
J Clin Psychiatry
November 2024
Northwestern University Feinberg School of Medicine, Asher Center for the Study and Treatment of Depressive Disorders, Chicago, Illinois.
Little is known about differences between Black and White women with respect to the prevalence of postpartum mood disorders or symptom presentations. To determine the prevalence and characteristics of postpartum major mood disorders in Black and White women at 4-6 weeks after birth. This is a secondary analysis of a large-scale study designed to screen women for postpartum depression with the Edinburgh Postnatal Depression Scale (EPDS) and collect symptom data.
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