Hypospadias is one of the common congenital malformations of the urogenital system in children, with a high incidence and an increasing trend. And the incidence rate of severe hypospadias is increasing year by year, which seriously affects the penile development of the patient. With deepened understanding of hypospadias, accumulated experience in its diagnosis and treatment, and continuous improvement of surgical strategies, the success rate of surgical repair of hypospadias has been elevated to a certain extent. However, quite a few problems remain to be studied, such as the high rate of complications, insufficient understanding of penile curvature, long-term follow-up recurrence of penile curvature, selection of strategic staged surgery, etc. This article analyzes the treatment of severe hypospadias and related problems, and provides some reference for clinicians in surgical repair of severe hypospadias.
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BMC Urol
January 2025
Urology Department HOGIP UCAD, Cheikh Anta Diop University, Dakar, Senegal.
Background: The inelasticity of dartos tissue and the regulation of collagen expression are significant factors in the pathophysiology of chordee associated with hypospadias. While the COL2A1:COL1A1 ratio is recognised as a measure of cell differentiation, there is yet to be a study specifically examining this ratio in hypospadias. The aim of this study was to determine the COL2A1:COL1A1 ratio.
View Article and Find Full Text PDFArch Ital Urol Androl
December 2024
Medical Doctor Study Program, Faculty of Medicine Universitas Udayana, Denpasar.
Purpose: Hypospadias, one of the congenital anomalies commonly associated with some degrees of ventral penile curvature that may arise from malformation of dartos fascia, the chordee. Our study aims to determine the correlation between the histopathology properties of dartos fascia and the severity of ventral penile curvature in hypospadias.
Materials And Methods: One hundred hypospadias patients with various degrees of ventral penile curvature were included in this cross-sectional analytical study from 2020 to 2022.
Int Urol Nephrol
December 2024
Department of Surgery, Division of Urology, Rutgers New Jersey Medical School, 185 South Orange Avenue, Newark, NJ, 07103, USA.
Introduction: Panurethral strictures represent the most severe form within the anterior urethral stricture spectrum, requiring more technically complex repairs and resulting in poorer outcomes compared to localized anterior urethral strictures (penile or bulbar). This abstract aims to describe the distinct characteristics of patients with panurethral strictures in a low socioeconomic status population.
Methods: Patients presenting with localized anterior (penile or bulbar) or panurethral strictures at University Hospital in Newark, NJ, between 2021 and 2023 were retrospectively identified.
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