AI Article Synopsis
- Differences in reference intervals for various dog breeds have been noted, highlighting the need for breed-specific data, especially for MDR1-deficient Collies.
- This study aimed to create plasma chemistry reference intervals specifically for adult MDR1-deficient Collies by analyzing samples from 110 healthy dogs.
- The findings revealed that the reference intervals for these Collies were similar to those established for Beagles, with little variation between male and female results.
Article Abstract
Background: Differences in the reference intervals between dog breeds have been recognized for many years. Due to the importance of multi-drug-resistance 1-deficient (MDR1) Collies in veterinary medicine, it is important to determine whether breed-specific reference intervals are needed for this group.
Objectives: The goal of this study was to establish plasma chemistry reference intervals for adult MDR1-deficient Collies.
Methods: Plasma samples collected from 110 healthy male and female adult MDR1-deficient Collies were analyzed for 21 analytes on a Beckman AU480 clinical chemistry analyzer. Reference intervals were established using a nonparametric statistical method.
Results: Reference intervals were established for 21 biochemical measurands in healthy adult MDR1-deficient Collies.
Conclusion: Plasma chemistry reference intervals for MDR1-deficient Collies were clinically similar to intervals earlier created for Beagles. Intervals for male and female MDR1-deficient Collies were very similar to each other.
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| http://dx.doi.org/10.1111/vcp.13286 | DOI Listing |
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