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Similar Publications

Pellagra: Is It Here or is It Rare?

J Assoc Physicians India

May 2024

Co-Chairman and Senior Consultant, Department of Internal Medicine, Sir Ganga Ram Hospital, Delhi, India.

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Article Synopsis
  • - Alcohol use disorder can lead to complications like pellagra, a rare condition that presents challenges in diagnosis, particularly in resource-poor settings.
  • - A case study of a 36-year-old male with a history of substance abuse revealed symptoms such as hallucinations and neurological deficits, ultimately diagnosed as alcoholic pellagrous encephalopathy (APE) linked to niacin deficiency.
  • - Recognizing atypical symptoms of APE in alcohol-dependent individuals is crucial; prompt diagnosis and treatment can improve outcomes, although socioeconomic factors may complicate timely intervention.
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The Pellagra Portraits.

JAMA

February 2024

Department of Medical History and Bioethics, School of Medicine and Public Health, University of Wisconsin, Madison.

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A Second Look at Niacin.

Skinmed

December 2023

EMD Electronics, Surface Solutions, Philadelphia, PA;

Article Synopsis
  • Niacin, known as vitamin B3, has a rich history in medicine and skin care, recognized for its nutritional and skin tone brightening properties.
  • It has been identified as potentially helpful in treating COVID-19 and in protecting the skin from the harmful effects of blue light.
  • Niacin is effective in managing various skin issues, including acne, reducing hyperpigmentation, and enhancing skin health through topical applications.
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Article Synopsis
  • - This report details a rare case of pellagra in a 60-year-old man with a history of chronic alcoholism, showcasing symptoms like a rash and diarrhea.
  • - Laboratory tests showed significant niacin deficiencies, confirming the diagnosis, and initiating niacin supplements and dietary changes improved the patient's condition.
  • - The case highlights the importance of recognizing the classic symptoms of pellagra—rash, diarrhea, and malnutrition—especially in individuals with alcohol use disorder for better health outcomes.
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