The association of focal motor seizures with cerebral hemiatrophy is a recognised rare paediatric syndrome known as 'hemiconvulsion, hemiatrophy and epilepsy' (HHE). To date, HHE has not been reported in adults. We present four adult patients with striking similarities to HHE, following alcohol withdrawal in chronic alcoholics. We document the imaging findings in the acute and subacute phases, discuss the underlying mechanisms and present a hypothesis regarding the pathophysiology.
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View Article and Find Full Text PDFArticle Synopsis
- Hemiconvulsion-hemiplegia-epilepsy (HHE) syndrome is a rare condition that causes one-sided seizures, brain tissue loss, and lifelong paralysis in some cases, often stemming from poorly managed seizure episodes in children.
- A 30-year-old male patient, previously undiagnosed, was suffering from uncontrolled seizures, phenytoin toxicity, and weakness on one side, leading to a diagnosis of HHE.
- The diagnosis was confirmed through specific imaging, which changed the treatment approach, allowing for various surgical options to be considered for this challenging condition.
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