Background: Electrocardiogram (ECG) is a powerful tool for studying cardiac activity and diagnosing various cardiovascular diseases, including arrhythmia. While machine learning and deep learning algorithms have been applied to ECG interpretation, there is still room for improvement. For instance, the commonly used Recurrent Neural Networks (RNNs), reply on its previous state to update and is therefore ineffective for parallel computing. RNN also struggles to efficiently address the issue of long-distance reliance.
Purpose: To reduce computational complexity by dimensionality reduction of ECG signals we constructed a Stacked Auto-encoders model using Transformer for ECG-based arrhythmia detection. And overcome the challenges of long-term dependencies and limited parallelizability in traditional RNNs when applied to ECG signal processing.
Methods: In this paper, a Transformer-Based ECG Dimensionality Reduction Stacked Auto-encoders model is proposed for ECG-based arrhythmia detection. The transformer is used to encode ECG signals into a feature matrix, which is then dimensionally reduced using unsupervised greedy training through the four linear layers. This resulted in a low-dimensional representation of ECG features, which are subsequently classified using support vector machines (SVM) to minimize overfitting.
Results: The proposed method is benchmarked on the MIT-BIH Arrhythmia database. In the 10-fold cross validation of beat-based arrhythmia detection, the average accuracy, sensitivity, specificity and F1 score of the proposed method are 99.83%, 98.84%, 99.84% and 99.13%, respectively, for the record-based arrhythmia detection which refers to the approach where the training and testing sets use ECG data from independent recorded patients are 88.10%, 49.79%, 91.56% and 39.95%, respectively.
Conclusions: Compared to other existing ECG-based arrhythmia detection methods, our proposed approach exhibits improved detection accuracy and stronger generalization for arrhythmia beats. Additionally, the use of the record-based data division method makes our approach more suitable for clinical practice.
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http://dx.doi.org/10.1002/mp.16534 | DOI Listing |
Europace
December 2024
Gottfried Schatz Research Center, Division of Medical Physics and Biophysics, Medical University of Graz, Graz, Austria.
In 1924, the Dutch physiologist Willem Einthoven received the Nobel Prize in Physiology or Medicine for his discovery of the mechanism of the electrocardiogram (ECG). Anno 2024, the ECG is commonly used as a diagnostic tool in cardiology. In the paper 'Le Télécardiogramme', Einthoven described the first recording of the now most common cardiac arrhythmia: atrial fibrillation (AF).
View Article and Find Full Text PDFPharmacy (Basel)
December 2024
R&D for Clinical Activity in Telemedicine, Italian National Health Agency-AGENAS, 00187 Rome, Italy.
Atrial fibrillation (AF) is one of the most common cardiac arrhythmias of clinical relevance and a major cause of cardiovascular morbidity and mortality. Following a diagnosis of AF, patients are directed towards therapy with anticoagulant drugs to reduce the thromboembolic risk and antiarrhythmics to control their cardiac rhythm, with periodic follow-up checks. Despite the great ease of handling these drugs, we soon realized the need for follow-up models that would allow the appropriateness and safety of these pharmacological treatments to be monitored over time.
View Article and Find Full Text PDFESC Heart Fail
December 2024
Department of Rehabilitation Medicine, China-Japan Friendship Hospital, Beijing, China.
Aims: Biomarkers are pivotal in the management of heart failure (HF); however, their lack of cardiac specificity could limit clinical utility. This study aimed to investigate the transcoronary changes and intracardiac production of these biomarkers.
Methods: Transcoronary gradients for B-type natriuretic peptide (BNP) and five novel biomarkers-galectin-3 (Gal-3), soluble suppression of tumourigenicity 2 (sST2), tissue inhibitor of metalloproteinase 1 (TIMP-1), growth differentiation factor 15 (GDF-15) and myeloperoxidase (MPO)-were determined using femoral artery (FA) and coronary sinus (CS) samples from 30 HF patients and 10 non-HF controls.
J Cardiovasc Dev Dis
December 2024
Cardiac Electrophysiology Division, Cardiology Center, Department of Internal Medicine, University of Szeged, 6725 Szeged, Hungary.
Background: An atrioventricular defibrillator system with a floating atrial dipole (VDD ICD) can provide atrial sensing by a single lead. Our aim was to compare the arrhythmia detection efficacy of VDD ICDs with conventional single- (VVI) and dual-chamber (DDD) defibrillators.
Methods: Data from consecutive patients undergoing ICD implantation were retrospectively analyzed.
Ann Noninvasive Electrocardiol
January 2025
Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong.
Background: Brugada syndrome (BrS) is an inherited channelopathy characterized by right precordial ST-segment elevation. This study investigates the clinical and genetic characteristics of children with BrS in Hong Kong.
Methods: A retrospective review was conducted at the only tertiary pediatric cardiology center in Hong Kong from 2002 to 2022, including all pediatric BrS patients under 18 years old.
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