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PTSD and depression severity are associated with cardiovascular disease symptoms in trauma-exposed women. | LitMetric

AI Article Synopsis

  • PTSD and depression are linked to a higher risk of cardiovascular disease (CVD), especially in women with a history of trauma.
  • This study examined the connections between cardiovascular health and symptoms of PTSD and depression in 49 individuals assigned female at birth, all of whom experienced significant trauma.
  • Results showed that trauma exposure correlated with higher blood pressure, and CVD symptoms were significantly related to PTSD, depression, and anhedonia, indicating a need for further research on how treating these mental health issues could affect CVD risk.

Article Abstract

Posttraumatic stress disorder (PTSD) and depression are associated with increased risk for cardiovascular disease (CVD), which is the leading cause of death and disability worldwide. Epidemiological studies have revealed these illnesses to be highly comorbid, particularly among women. In the current study, we explored associations between indices of cardiovascular health, PTSD, and depression among a sample of trauma-exposed individuals assigned female at birth. Participants were  = 49 individuals without CVD who reported lifetime Criterion A trauma exposure. Blood pressure (BP), heart rate (HR), and high-frequency heart rate variability (HF-HRV) were collected during a 5-minute resting period. Symptoms of CVD (e.g. extremity pain and swelling, shortness of breath), PTSD, and depression were assessed, along with an exploratory measure of anhedonia. Trauma exposure was positively correlated with systolic BP ( = .32,  = .029) and diastolic BP ( = .30,  = .040). The number of reported CVD symptoms was positively correlated with symptoms of PTSD ( = .41,  = .004), depression ( = .40,  = .005) and anhedonia ( = .38,  = .007). CVD symptoms were also significantly associated with PTSD ( = .41,  = 2.43, = .023), depression ( = .40,  = 2.76, = .009), and anhedonia ( = .38,  = 2.51, = .017) after controlling for age and trauma exposure. These associations were not moderated by HF-HRV in our sample. Our results support the association between PTSD and depressive symptoms and worse cardiovascular functioning among an often-overlooked population that is particularly vulnerable to these illnesses. Future studies should investigate residual impacts of PTSD and depression treatment on CVD risk among trauma-exposed individuals, particularly women.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360993PMC
http://dx.doi.org/10.1080/20008066.2023.2234810DOI Listing

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