Much of the U.S. adult population will experience a traumatic event at some point in their lives, resulting in about 20 million people developing posttraumatic stress disorder (PTSD) and costing over $143 billion for healthcare. The Community Resilience Model (CRM) and Mental and Emotional Self-Management (MESM) are potential novel solutions for stemming the tide of PTSD diagnoses resulting from a traumatic event. This pilot study was conducted to examine the phasic and tonic changes in cardiac vagal tone in a non-traumatized sample population ( = 83) after a 1-week intervention. Group comparisons were conducted between the CRM ( = 26), MESM ( = 34), and Control ( = 23) conditions. Participants ranged in age from 18 to 30. A phasic effect on cardiac vagal tone was found for the MESM condition within subjects but not for the CRM or control conditions. A tonic effect on cardiac vagal tone was not found within subjects amongst the three conditions. The phasic effect in the MESM condition was significantly different between itself and the CRM and control groups. No tonic effects on cardiac vagal tone were found between conditions either. These results suggest cardiac vagal tone responds to focused breathing in the moment only, but more research with larger sample sizes, longer intervention duration, and better methods to track home practice compliance are needed before one accepts the insignificant results as valid. This pilot study can serve as an introduction to the study of physiological processes that might be trainable to increase resilience in non-traumatized populations and serve as a springboard for future studies of physiological resilience to traumatic stress.
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http://dx.doi.org/10.3389/fpsyg.2023.1144302 | DOI Listing |
J Clin Med
December 2024
UOC Allergologia-Asma Center, University of Verona, 37129 Verona, Italy.
Benralizumab is an anti-IL-5 receptor alpha monoclonal antibody that induces the near-complete depletion of eosinophils. This study aimed to evaluate the long-term safety and effectiveness of benralizumab in patients with severe eosinophilic asthma (SEA) over an extended 48-month follow-up period, offering one of the longest real-world perspectives available. This was a single-arm, retrospective, observational, multicenter study involving 123 SEA patients treated with benralizumab at a dosage of 30 mg every 4 weeks for the first 3 doses and then every 8 weeks.
View Article and Find Full Text PDFWidespread vagal activation following honey consumption is a sign of mad honey poisoning. Early initiation and appropriate treatment can prevent fatal outcomes.
View Article and Find Full Text PDFPrev Nutr Food Sci
December 2024
Department of Sports Science, Faculty of Sports and Health Science, Kasetsart University, Nakhon Pathom 73140, Thailand.
Chicken essence (CE) is known for its antihypertensive properties. However, few studies have investigated the effects of CE in prehypertensive individuals. Here, we conducted a randomized crossover clinical trial on prehypertensive offspring of hypertensive parents to evaluate the effects of preworkout CE consumption (CEC) on post-exercise hypotension (PEH) and cardiac autonomic and vascular responses.
View Article and Find Full Text PDFScand J Pain
January 2024
Crean College of Health and Behavioral Sciences, Department of Physical Therapy, Chapman University, Irvine, United States.
Objectives: Autonomic regulation has been identified as a potential regulator of pain via vagal nerve mediation, assessed through heart rate variability (HRV). Non-invasive vagal nerve stimulation (nVNS) and heart rate variability biofeedback (HRVB) have been proposed to modulate pain. A limited number of studies compare nVNS and HRVB in persons with chronic pain conditions.
View Article and Find Full Text PDFNat Rev Cardiol
January 2025
Institute for Pathophysiology, West German Heart and Vascular Center, University of Duisburg-Essen, Essen, Germany.
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