Two sibling mandrills with clinical evidence of lead intoxication showed previously unreported hepatic alterations. The younger animal had high lead concentrations in blood, kidneys, and liver and characteristic intranuclear inclusions in renal tubules and hepatocytes. The liver showed diffuse nodular regenerative hyperplasia. The older mandrill had high lead concentrations in blood only and resolving intranuclear inclusions in liver and kidneys. The liver showed prominent portal fibrosis with evidence of resolving diffuse nodular hyperplasia. Occipital horn hydrocephalus was also present.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
diffuse nodular
12
nodular hyperplasia
8
high lead
8
lead concentrations
8
concentrations blood
8
kidneys liver
8
intranuclear inclusions
8
liver
5
hyperplasia fibrosis
4
fibrosis liver
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!