This study represents the first national survey conducted in Sri Lanka to establish national diagnostic reference levels (NDRLs) for screening and diagnostic acquisitions in digital mammography (2D-DM) and digital breast tomosynthesis (DBT). Additionally, the study investigated the relationship between average glandular dose (AGD) and compressed breast thickness (CBT) and introduced a novel concept called dose range bands (DRBs) as a tool for optimizing radiation dose in mammography. DICOM metadata was used to extract dose data and exposure parameters from women undergoing either screening (350) or diagnostic (750) DM. The analysis included both craniocaudal and mediolateral oblique views of each breast, acquired using 2D-DM and DBT imaging techniques. The NDRL (AGD per view) was 1.97 mGy and 2.01 mGy for diagnostic DM and DBT, respectively. The corresponding NDRLs for screening acquisition were 2.44 mGy and 2.30 mGy. The mean DBT/DM AGD ratio was 1.39 and 0.97 for diagnostic and screening, respectively. Further, the association between the average glandular AGD per view and CBT is stronger in DBT than in 2D-DM. The study findings highlight the need for standardisation of compression practices, considering factors such as the radiographer's experience, imaging equipment, breast density, age, breast size, and pain threshold.
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http://dx.doi.org/10.1088/1361-6498/ace833 | DOI Listing |
Cont Lens Anterior Eye
December 2024
Department of Ophthalmology, Molecular Pharmacology and Physiology, FL, United States; Pathology and Cell Biology, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Purpose: To evaluate the efficacy and safety of topical Ivermectin- Metronidazol in the management of demodex infestation and their effect in Meibomian gland dysfunction (MGD) METHODS: Fifty-four patients (108 eyes) with demodex diagnosis and Meibomian gland dysfunction received Ivermectin 0.3 %+Metronidazole 0.5 % gel in the night for 5 weeks.
View Article and Find Full Text PDFSurg Innov
December 2024
Department of Plastic and Reconstructive Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Background: Gynecomastia, the enlargement of male breast tissue, significantly impacts both physical and psychological health. Surgical intervention is often necessary, utilizing various techniques to reduce glandular and fatty tissue. This paper introduces an innovative surgical method combining power-assisted liposuction with the stab-flatten technique to enhance precision and cosmetic results.
View Article and Find Full Text PDFDiagnostics (Basel)
November 2024
Faculty of Applied Science, Uplands College of Science and Technology Incorporated (UCSI), Kuala Lumpur 56000, Malaysia.
Sichuan Da Xue Xue Bao Yi Xue Ban
September 2024
( 610041) Department of Pathology, West China Hospital, Sichuan University, Chengdu 610041, China.
Objective: To investigate the clinicopathological features, immunophenotypes, molecular genetic alterations, and prognosis of succinate dehydrogenase-deficient renal cell carcinoma (SDH-RCC).
Methods: A total of 11 cases of SDH-RCC diagnosed at West China Hospital, Sichuan University between 2016 and 2023 were selected for clinicopathological, immunohistochemical, and DNA sequencing analyses.
Results: Among the 11 cases of SDH-RCC, there were 5 male patients and 6 female patients.
Reprod Sci
December 2024
Department of Pathology and Laboratory Medicine, University of Wisconsin - Madison, Madison, Wisconsin, USA.
The GATA gene family encodes highly conserved zinc-finger transcription factors that facilitate the development and function of multiple organ systems including the uterus. In the endometrium, GATA2 functions in a positive autoregulatory loop with the progesterone receptor (PGR) and colocalizes with PGR on chromatin to promote PGR transcriptional programs. GATA2 also has PGR-independent functions that maintain endometrial cell identity, and GATA2 transcripts reportedly are down-regulated in endometrial disorders including endometriosis.
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