In this work, we developed a facile and controllable electrophilic aromatic nitration method with commercially available 68% HNO as the nitrating reagent and trifluoromethanesulfonic acid (HOTf) as the catalyst in hexafluoroisopropanol or under solvent-free conditions. The electrophilic nitration products of different arenes can be obtained in almost quantitative yields by tuning the loading of HOTf. The strong acidity and water absorbing property of HOTf allowed this transformation to reach completion in a short time at room temperature.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.joc.3c00892 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Triflic Acid-Mediated Chemoselective Indole C2-Heteroarylation of Peptide Tryptophan Residues by Triazine.
Org Lett
December 2024
Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, 510006 Guangzhou, Guangdong, China.
Article Synopsis
- Peptide modification allows for the creation of peptides with specific functions, and tryptophan is a prime candidate due to its unique chemical properties.* -
- The study presents a new method for modifying tryptophan and indole derivatives without using transition metals, utilizing triazine derivatives activated by triflic acid.* -
- The new functional group introduced can be used for further chemical reactions, specifically an inverse electron demand Diels-Alder reaction, enabling additional bioconjugation opportunities.*
A Facile Strategy for In Situ Fabrication of Covalent Triazine Framework Aerogel with Thermal Insulation Property.
ACS Appl Mater Interfaces
December 2024
Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, School of Chemistry and Chemical Engineering, Zhejiang Sci-Tech University, Hangzhou 310018, PR China.
Covalent triazine frameworks (CTFs) have attracted tremendous attention with respect to their rich nitrogen content, functional triazine units, and high porosity. However, efficient and simple preparation of CTF monoliths is still a challenge. Here, we propose a novel and facile approach for the in situ preparation of CTF aerogels.
View Article and Find Full Text PDFRoom-Temperature Formate Ester Transfer Hydrogenation Enables an Electrochemical/Thermal Organometallic Cascade for Methanol Synthesis from CO.
Angew Chem Int Ed Engl
November 2024
Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-3290, United States.
The reduction of CO to synthetic fuels is a valuable strategy for energy storage. However, the formation of energy-dense liquid fuels such as methanol remains rare, particularly under low-temperature and low-pressure conditions that can be coupled to renewable electricity sources via electrochemistry. Here, a multicatalyst system pairing an electrocatalyst with a thermal organometallic catalyst is introduced, which enables the reduction of CO to methanol at ambient temperature and pressure.
View Article and Find Full Text PDFInterface engineering enabling thin lithium metal electrodes down to 0.78 μm for garnet-type solid-state batteries.
Nat Commun
November 2024
Key Laboratory for Advanced Ceramics and Machining Technology of Ministry of Education, School of Materials Science and Engineering, Tianjin University, Tianjin, China.
Controllable engineering of thin lithium (Li) metal is essential for increasing the energy density of solid-state batteries and clarifying the interfacial evolution mechanisms of a lithium metal negative electrode. However, fabricating a thin lithium electrode faces significant challenges due to the fragility and high viscosity of Li metal. Herein, through facile treatment of Ta-doped LiLaZrO (LLZTO) with trifluoromethanesulfonic acid, its surface LiCO species is converted into a lithiophilic layer with LiCFSO and LiF components.
View Article and Find Full Text PDFEnvironmental Occurrence and Biotic Concentrations of Ultrashort-Chain Perfluoroalkyl Acids: Overlooked Global Organofluorine Contaminants.
Environ Sci Technol
December 2024
Department of Civil and Environmental Engineering, Colorado School of Mines, Golden, Colorado 80401, United States.
Article Synopsis
- PFASs are a group of man-made chemicals, and ultrashort-chain PFAAs have become a focus due to their environmental impact and prevalence.
- A literature database from 1990 to 2024 reveals that these ultrashort-chain PFAAs, particularly TFA, are widely found in various environments and often at higher concentrations than longer-chain PFASs.
- The review also indicates that ultrashort-chain PFAAs are present in many living organisms, including humans, and emphasizes the need for research and regulation due to their increasing significance in environmental health discussions.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!