We report a case of a 40-year-old male who had the clinical signs of chronic migraine. The diagnosis of chronic migraine is based on International Headache Society diagnostic criteria. The patient was bothered by unilateral and localized pain in the frontotemporal and ocular area, which lasts 4-72 hours, sensitivity to light and sound. Headache has pulsating quality, moderate or severe pain intensity. Attacks of headache bothered about 15-20 days a month. According to the standard MR scanning protocol, single areas of increased MR signal were detected in the mode Т2, Flair, which do not limit diffusion and do not cause a change in the MR signal in the SWI mode. The foci are located subcortically in the white matter of the frontal lobes of the brain, corresponding to foci of gliosis of the white matter of the frontal lobes. The patient received antiepileptic drugs, β-Blockers, triptans, antidepressants.The patient is recommended to inject botulinum toxin.
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http://dx.doi.org/10.36740/WLek202306125 | DOI Listing |
Eur J Neurosci
January 2025
Faculty of Medicine, Collegium Medicum, Mazovian Academy in Plock, Plock, Poland.
Chronic migraine (CM) is the ultimate and most burdensome form of the transformation from episodic migraine (EM), called chronification. The mechanism behind migraine chronification is poorly known and difficult to explore as CM has the same spectrum of pathogenesis as EM and the EM-CM transition is bidirectional. Central sensitization (CS) is a key phenomenon in migraine: its mechanisms include disturbed neural plasticity, which is the ability of the nervous system to adapt to endo- and exogenous changes.
View Article and Find Full Text PDFSAGE Open Med
January 2025
Tufts University School of Medicine, Boston, MA, USA.
Objective: This study utilized a sample of trangender, nonbinary, and gender-diverse (TGD) patients to build on emerging literature that suggests that hypermobile Ehlers-Danlos syndrome may be overrepresented in TGD populations. The objective of this retrospective chart review was to determine the prevalence of hypermobile Ehlers-Danlos syndrome syndrome at a gender-affirming primary care clinic.
Methods: A retrospective chart review of medical records was conducted with records between May 2021 and June 2024.
Front Pharmacol
January 2025
Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Background: Migraine represents a chronic neurological disorder characterized by high prevalence, substantial disability rates, and significant economic burden. Its pathogenesis is complex, and there is currently no cure. The rapid progress in multi-omics technologies has provided new tools to uncover the intricate pathological mechanisms underlying migraine.
View Article and Find Full Text PDFExplore (NY)
January 2025
Suchangdang Korean Medicine Clinic, Seoul 06084, Republic of Korea.
Background: Migraine is a neurological disorder characterized by severe, unilateral, pulsating headaches with visual, olfactory, and auditory hypersensitivity, as well as autonomic symptoms. Currently, triptans are the standard treatment, but they often fail to relieve symptoms. Herbal medicines are alternative treatments to overcome these limitations.
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