AI Article Synopsis
- - Treatment of late-onset neonatal staphylococcal sepsis can be difficult due to potential side effects of vancomycin and concerns about managing catheters.
- - In a study, ceftaroline was given as a compassionate treatment to 16 infants (under 32 weeks gestational age and less than 28 days old) after their initial treatment failed.
- - The results showed 11 successful outcomes with no serious adverse drug reactions, but more extensive research is needed to validate these promising findings.
Article Abstract
Treatment of late-onset neonatal staphylococcal sepsis is sometimes challenging with feared side effects of vancomycin, increasing minimal inhibitory concentrations and questions about catheter management. In case of failure, ceftaroline was administered as a compassionate treatment in 16 infants (gestational age of less than 32 weeks and less than 28 postnatal days), whose first-line treatment failed. We report 11 successes and no severe adverse drug reactions. Larger data are required to confirm these encouraging results.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/INF.0000000000004023 | DOI Listing |
Publication Analysis
Top Keywords
safety efficacy
4
efficacy ceftaroline
4
ceftaroline neonates
4
neonates staphylococcal
4
staphylococcal late-onset
4
late-onset sepsis
4
sepsis case
4
case series
4
series analysis
4
analysis treatment
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!