Morphologically controllable ALG@ε-PL water-in-water microspheres were successfully prepared using a two-step method through precise control of the two-phase flow rate. Through further interfacial coagulation, the ALG@ε-PL microspheres possess a dense surface structure and good permeability. The sensor based on PtS@ALG@ε-PL microspheres was constructed by encapsulating PtS nanosheets with peroxidase-like properties in ALG@ε-PL water-in-water microspheres. PtS nanosheets catalyze the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) by HO to produce blue oxTMB. The strong reducing property of the model analyte dopamine (DA) can reduce oxTMB, thus causing the blue color to fade and successfully achieving colorimetric detection of DA. The linear range of the assay is 2.0-200 μM, and the detection limit is 0.22 μM. The recoveries of DA in serum samples were determined by the spik method, and the results were reproducible.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00604-023-05876-y | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Peroxidase-mimicking poly-L-lysine/alginate microspheres with PtS nanoparticles for image-based colorimetric assays.
Mikrochim Acta
July 2023
Department of Chemistry, Key Laboratory of Biomedical Functional Materials, School of Science, China Pharmaceutical University, 638 Longmian Avenue, Chunhua Street, Jiangning District, Nanjing, 211198, People's Republic of China.
Morphologically controllable ALG@ε-PL water-in-water microspheres were successfully prepared using a two-step method through precise control of the two-phase flow rate. Through further interfacial coagulation, the ALG@ε-PL microspheres possess a dense surface structure and good permeability. The sensor based on PtS@ALG@ε-PL microspheres was constructed by encapsulating PtS nanosheets with peroxidase-like properties in ALG@ε-PL water-in-water microspheres.
View Article and Find Full Text PDFPtS nanosheets as a peroxidase-mimicking nanozyme for colorimetric determination of hydrogen peroxide and glucose.
Mikrochim Acta
April 2021
School of Science, Key Laboratory of Biomedical Functional Materials, China Pharmaceutical University, Nanjing, People's Republic of China.
Using an ultrasonication-assisted liquid exfoliation method, we have synthesized PtS nanosheets with good reproducibility. Herein, intrinsic peroxidase-like activity was for the first time demonstrated for PtS nanosheets, which can catalyze HO oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) to generate a colored solution. The catalytic mechanism of PtS nanosheets was investigated, which indicated that acceleration of the electron transfer between TMB and HO was the main reason for the peroxidase-like activity of PtS nanosheets.
View Article and Find Full Text PDFRetrospective European Multicentric Evaluation of Selective Transarterial Chemoembolisation with and without Balloon-Occlusion in Patients with Hepatocellular Carcinoma: A Propensity Score Matched Analysis.
Cardiovasc Intervent Radiol
July 2021
Department of Interventional Radiology, Gustave Roussy Cancer Center, Villejuif, France.
Purpose: The aim of this retrospective multicentric study was to compare the tumour response rates of Balloon-occluded Transarterial Chemoembolisation (B-TACE) to non-B-TACE using propensity score matching (PSM) in patients with hepatocellular carcinoma and to investigate the clinical benefit, such as lower rates of TACE re-intervention achieved using B-TACE.
Material And Methods: The B-TACE procedures (n = 96 patients) were compared with a control group of non-B-TACE treatments (n = 434 pts), performed with conventional (cTACE) or drug-eluting microspheres TACE (DEM-TACE). Data were collected from six European centres from 2015 to 2019.
Safety Profile and Efficacy of Chemoembolization with Doxorubicin - Loaded Polyethylene Glycol Microspheres in Patients with Hepatocellular Carcinoma.
Open Access Maced J Med Sci
March 2019
Department for Gastroenterology and Hepatology, General City Hospital 8th September, Skopje, Republic of Macedonia.
Aim: This study was designed as a preliminary investigation of safety and efficacy of LifePearl, polyethylene glycol microspheres loaded with doxorubicin for treatment of locally untreatable (i.e., unresectable and not suitable for local thermal ablation) hepatocellular carcinoma (HCC).
View Article and Find Full Text PDFCellulose microspheres-filled pipet tips for purification and enrichment of glycans and glycopeptides.
J Chromatogr A
September 2018
Britton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics, Hubei Bioinformatics & Molecular Imaging Key Laboratory, Systems Biology Theme, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China. Electronic address:
The pretreatment of low-abundance glycans/glycopeptides prior to mass spectrometry (MS) analysis is of great significance for glycosylation identification of proteins. Herein, a simple one-step purification and enrichment procedure of glycans and glycopeptides was achieved using cellulose microspheres-filled pipet tips (CM-PTs). CM-PTs were fabricated by conveniently filling cellulose microspheres synthesized by sol-gel transition method into 100 μL pipet tips.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!