AI Article Synopsis
- A case-control study in China investigates the connection between Toxoplasma gondii infection and rheumatic diseases, revealing higher infection rates in rheumatic patients compared to controls (17.25% vs. 10.70%).
- The study found no significant differences in T. gondii seroprevalence among different types of rheumatic conditions, nor was disease duration linked to infection rates.
- Three risk factors associated with higher T. gondii seroprevalence were identified: having cats at home, a history of blood transfusions, and consuming raw shellfish, highlighting the need for increased awareness in rheumatic patient care.
Article Abstract
Toxoplasma gondii infection in clinical cases of rheumatic diseases is increasing, whereas, the relationship between T. gondii infection and rheumatic diseases is still ambiguous and contradictory. Thus, the present case-control study based on serological diagnosis was carried out to identify the underlying relationship between T. gondii infection and rheumatic diseases in China. Serological results showed that rheumatic patients (17.25%, 79/458) had a significantly higher T. gondii seroprevalence than control subjects (10.70%, 49/458) (p = 0.004). However, the difference in T. gondii seroprevalence among clinical rheumatic disease forms was insignificant. Moreover, disease duration not effect the T. gondii seroprevalence in the included clinical rheumatic patients. Three risk factors (presence of cats at home, blood transfusion history, and consumption of raw shellfish) were identified through multivariate analysis to affect the T. gondii seroprevalence in the included clinical rheumatic patients. In conclusion, these results indicate that the latent T. gondii infection in clinical rheumatic patients should cause alarm and attention in the course of future scientific research or clinical treatment.
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| http://dx.doi.org/10.1016/j.micpath.2023.106257 | DOI Listing |
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