Objective: To investigate the clinical effect of biofeedback and electrical stimulation therapy (BFES) combined with Sabale capsules (SC) on chronic prostatitis / chronic pelvic pain syndrome (CP/CPPS).
Methods: A total of 140 outpatients meeting CP/CPPS diagnostic and research criteria in the Second Affiliated Hospital of Xi'an Jiaotong University were randomly divided into groups A (blank control), B (BFES intervention), C (SC intervention) and D (BFES+SC intervention), 35 cases in each group. The patients in group A were left untreated, while those in groups B, C and D received BFES, SC and BFES+SC, respectively, all for 12 weeks. Then the patients were followed up at 30 days after treatment and the urinary flow rate and NIH-CPSI scores were obtained and compared with the baseline.
Results: In comparison with the baseline, the total NIH-CPSI scores after intervention were significantly decreased in groups B, ([27.30 ± 2.44] vs [19.43 ± 2.33]), C ([26.77 ± 2.54] vs [19.40 ± 2.75]) and D ([27.67 ± 3.69] vs [15.57 ± 1.94]) (all P < 0.05), and so were the individual item scores in pain or discomfort ([12.50 ± 1.94] vs [9.40 ± 2.01], [11.93 ± 1.64] vs [9.23 ± 1.96], and [12.33 ± 2.20] vs [7.50 ± 1.55]), urination symptoms ([6.07 ± 1.57] vs [3.83 ± 1.05], [5.97 ± 1.33] vs [3.77 ± 1.14], and [6.20 ± 1.88] vs [2.87 ± 0.94]), quality of life (QOL) ([8.73 ± 1.62] vs [6.20 ± 1.42], [8.87 ± 1.25] vs [6.40 ± 1.59], and [9.13 ± 1.70] vs [5.20 ± 1.40]) (all P < 0.05), while the maximum urinary flow rate (Qmax) was remarkably increased ([15.72 ± 2.38] vs [19.73 ± 2.85], [16.20 ± 2.44] vs [19.46 ± 2.48], and [15.83 ± 2.52] vs [22.49 ± 2.76]) (all P < 0.05), and so was the average urinary flow rate (Qavg) ([9. 282 ± 1.52] vs [11.27 ± 1.95], [8.97 ± 1.25] vs [11.16 ± 1.74], and [9.20 ± 1.36] vs [13.50 ± 2.30]) (all P < 0.05). The decrease in NIH-CPSI total and item scores and increase in Qmax and Qavg after treatment were more significant in group D than in B and C (P < 0.05), but showed no statistically significant difference between groups B and C (P > 0.05). Nor was any significant change observed in the above parameters in group A after treatment ( P > 0.05).
Conclusions: Biofeedback and electrical stimulation therapy combined with Sabale capsules can alleviate urination dysfunction, pelvic floor tension myalgia and other symptoms and significantly improve the QOL of CP/CPPS patients.
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