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Ultra high-speed single-molecule fluorescence imaging. | LitMetric

Ultra high-speed single-molecule fluorescence imaging.

J Cell Biol

Mechanobiology Institute, National University of Singapore, Singapore, Republic of Singapore.

Published: August 2023

AI Article Synopsis

  • Fujiwara et al. created a high-speed camera that can capture single-molecule fluorescence images at a microsecond level.
  • This innovation significantly enhances detection speed, allowing for detailed observation of plasma membrane organization.
  • The research focuses on integrin-based adhesions, providing a new understanding of cellular interactions.

Article Abstract

In two articles in this issue, Fujiwara et al. developed an ultrasensitive high-speed camera capable of single-molecule fluorescence imaging at a microsecond timescale (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202110160). This major leap in detection speed enables the organization of plasma membrane and integrin-based adhesions to be probed in unprecedented detail (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202110162).

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351246PMC
http://dx.doi.org/10.1083/jcb.202306136DOI Listing

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