AI Article Synopsis
- - Trichomoniasis is a common and curable sexually transmitted infection, and accurate diagnosis is crucial for treatment to prevent complications and spread.
- - A study involving 1974 women used vaginal swabs to compare traditional diagnostic methods (wet microscopy and culture) with a polymerase chain reaction (PCR) test for better detection of the infection.
- - The results showed PCR was more sensitive (detecting additional cases) and had strong agreement with conventional methods, emphasizing PCR's value in screening symptomatic females for trichomoniasis.
Article Abstract
Introduction: Trichomoniasis remains one of the most common sexually transmitted infections, which is curable. To prevent complications and transmission, prompt and correct diagnosis is essential to treat . The present study was done to evaluate polymerase chain reaction (PCR) with other conventional techniques for the diagnosis of infection and determine the prevalence of in women with vaginal discharge based on PCR assay.
Methods: Vaginal swabs were collected by the trained health-care professional using FLOQSwabs™ (Copan, Italy) during routine pelvic examinations among 1974 symptomatic females. The wet microscopy, culture, and PCR were performed.
Results: The sensitivity of wet mount and culture in comparison to PCR was 60.87% and 56.52%, respectively. The kappa inter-rater agreement of PCR showed substantial agreement with wet mount microscopy (κ = 0.742) and culture (κ = 0.707). The PCR detected an additional 17 cases that were missed by conventional techniques.
Discussion: The study highlights the importance of PCR for screening among symptomatic females.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343104 | PMC |
| http://dx.doi.org/10.4103/ijstd.ijstd_21_22 | DOI Listing |
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