Unilateral Lung Agenesis: A Case Series and Review of Literature.

AJP Rep

Division of Neonatology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin.

Published: July 2023

Unilateral lung agenesis is a rare congenital abnormality that typically presents with respiratory distress after birth. Prognostic factors include the side of the lung affected along with the presence or absence of other congenital abnormalities. Prenatal imaging can make the diagnosis that can assist the healthcare team in preparing to care for the neonate, as well as set expectations for the family. In this case series, we describe three cases of unilateral lung agenesis, two infants with right lung agenesis, and one with the left. We describe their presentation, provide a brief clinical course, and discuss outcomes.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348820PMC
http://dx.doi.org/10.1055/a-2107-0651DOI Listing

Publication Analysis

Top Keywords

lung agenesis
16
unilateral lung
12
case series
8
agenesis
4
agenesis case
4
series review
4
review literature
4
literature unilateral
4
lung
4
agenesis rare
4

Similar Publications

Disruption of developmental processes affecting the fetal lung leads to pulmonary hypoplasia. Pulmonary hypoplasia results from several conditions including congenital diaphragmatic hernia (CDH) and oligohydramnios. Both entities have high morbidity and mortality, and no effective therapy that fully restores normal lung development.

View Article and Find Full Text PDF

Unique imaging observations in an incidentally detected bilateral upper lobe agenesis.

BMJ Case Rep

November 2024

Radiology, Narayana Hrudayalaya Health City Bangalore, Bengaluru, Karnataka, India

Article Synopsis
  • - Bilateral upper lobe pulmonary agenesis is a rare birth defect typically discovered incidentally in adults, with non-specific and subtle findings on traditional x-rays.
  • - Diagnosis is often missed on regular radiography, but chest CT scans performed for other reasons can reveal this condition.
  • - Contrast-enhanced CT is the best method for diagnosing and detailing the features of pulmonary agenesis, and understanding related pulmonary anomalies is crucial in treating patients with congenital heart issues.
View Article and Find Full Text PDF

Purpose: Amniotic fluid stem cell extracellular vesicles (AFSC-EVs) hold regenerative potential to treat hypoplastic lungs secondary to congenital diaphragmatic hernia (CDH). This study aims to investigate sex-specific differences in pulmonary hypoplasia severity and responses to AFSC-EV administration in an experimental CDH mouse model.

Methods: C57BL/6J dams were fed with nitrofen + bisdiamine (left-sided CDH) or olive oil only (control) at embryonic day (E) 8.

View Article and Find Full Text PDF

Pulmonary agenesis (PA) is a rare developmental malformation, with a frequency of approximately 1 in 10-15,000 pregnancies. Unilateral PA is often associated with other congenital anomalies, whereas bilateral PA is fatal. Prenatal diagnosis is rare and is diagnosed more frequently in the postnatal period than in the prenatal period.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!