The relationship between trauma and psychosis is complex and multifaceted, with evidence suggesting that trauma can be both a risk factor for the development of psychosis and a consequence of psychotic experiences. The present review aimed to provide an overview of the current state of knowledge on the relationship between trauma and psychosis, including historical and conceptual considerations, as well as epidemiological evidence. The potential explanation of the link between trauma and psychosis is provided through available models and similarities in their neurobiological associations. Overall, the research confirms the relationship between trauma and psychosis, and suggests that individuals with a co-occurring history of trauma and psychosis may have increased symptom severity and worse functional outcomes compared with individuals with psychosis alone. Future research should focus on elucidating the underlying causal pathways between trauma exposure and psychosis in order to inform effective treatment approaches aiming to prevent the intensification of psychotic symptoms and processes.
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http://dx.doi.org/10.3892/etm.2023.12085 | DOI Listing |
This case report explores the interplay between childhood trauma, social phobia, psychotic symptoms, and minority stress in a 27-year-old transgender male. L presented with psychotic symptoms, including auditory verbal hallucinations and self-referential phenomena, which were accompanied by a history of childhood sexual and emotional abuse, as well as social phobia. These challenges were further compounded by experiences of stigma, rejection, and stress related to his gender identity.
View Article and Find Full Text PDFNat Ment Health
January 2025
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.
While numerous reviews have assessed the association between traumatic brain injury (TBI) and various mental and physical health outcomes, a comprehensive evaluation of the scope, validity, and quality of evidence is lacking. Here we present an umbrella review of a wide range of health outcomes following TBI and outline outcome risks across subpopulations. On 17 May 2023, we searched Embase, Medline, Global Health, PsycINFO, and Cochrane Database of Systematic Reviews for systematic reviews and meta-analyses.
View Article and Find Full Text PDFSchizophrenia (Heidelb)
January 2025
Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL, USA.
J Interpers Violence
January 2025
Social and Education Sciences Department, School of Arts and Sciences, Lebanese American University, Jbeil, Lebanon.
The study objectives were to test the hypothesis that childhood trauma moderates the associations between early maladaptive schemas (EMS) and intimate partner violence (IPV) among women in the specific Lebanese patriarchal context. This is a cross-sectional study that was conducted on Lebanese women between September and December 2018; 1,655 participants enrolled in this study were from all of Lebanon's governorates and were selected using an equitable representative sample. The "Disconnection and Rejection" EMS domain showed the strongest correlations with both physical and nonphysical IPV ( = .
View Article and Find Full Text PDFSchizophr Bull
January 2025
Department of Psychiatry, UT Southwestern Medical Center, Dallas, TX 75390, United States.
Background: Investigations of causal pathways for psychosis can be guided by the identification of environmental risk factors. A recently developed composite risk tool, the exposome score for schizophrenia (ES-SCZ), which controls for intercorrelations between risk factors, has shown fair to good performance. We tested the transdiagnostic psychosis classifier performance of the ES-SCZ with the Bipolar-Schizophrenia Network for Intermedial Phenotypes data and examined its relationship with clinical-level outcomes.
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