Wells Syndrome with Generalized Oedema.

Eur J Case Rep Intern Med

First Internal Medicine Department, "Sismanoglio" General Hospital, Athens, Greece.

Published: June 2023

Unlabelled: Wells syndrome or eosinophilic cellulitis is a rare and relapsing skin disease which lacks systemic involvement. A skin biopsy is needed to establish a diagnosis. Several precipitating factors have been proposed but no proven causative link has been found. On the other hand, Churg-Strauss syndrome, also known as eosinophilic granulomatosis with polyangiitis (EGPA), an auto-immune disease, is associated with multiorgan, including cutaneous manifestations. We report a case with overlapping features of Wells and Churg-Strauss syndrome, suggesting that these syndromes could be part of the same nosological entity.

Learning Points: Biopsies are essential to establish a diagnosis in unusual cases of cellulitis.COVID-19 vaccination is a putative trigger for Wells syndrome.There is significant overlap between Wells and Churg-Strauss syndromes.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348442PMC
http://dx.doi.org/10.12890/2023_003954DOI Listing

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