Emergency vehicle crashes, involving police vehicles, ambulances, and fire trucks, pose a serious traffic safety concern causing severe injury and deaths to first responders and other road users. However, limited research is available focusing on the contributing factors and their interactions related to these crashes. This research aims to address this gap by 1) identifying patterns of emergency vehicle crashes based on severity levels in both emergency and non-emergency modes and 2) comparing the associations by response modes for the related fatal, nonfatal injury, and no-injury crashes. Two national crash databases, Fatality Analysis Reporting System (FARS) and Crash Report Sampling System (CRSS), were utilized for police-reported emergency vehicle crashes from January 2016 to February 2020. Association rule mining (ARM) was employed to reveal the association between factors that strongly contributed to these crashes. The generated rules were validated using the lift increase criterion (LIC). The results showed the complex nature of risk factors influencing the severity of emergency vehicle crashes. The fatal consequences of speeding with no seatbelt usage were evident for emergency mode, whereas none of these risky driving attributes was observed for non-emergency mode. In addition, the analysis identified the risk of fatal emergency vehicle crashes involving pedestrians in dark-lighted conditions in both response modes. Regarding nonfatal injury severity, angle collisions were more likely to occur at urban intersections during emergencies, while rear-end crashes were more frequent on segments with a posted speed limit of 40-45 mph during non-emergency incidents. The outcomes also revealed that the no-injury crashes involving fire trucks exhibited different patterns depending on the response mode. The findings of this study can guide in making effective strategies to improve safe driving behavior of first responders. The identified associations provide insights into the factors that can be controlled to ensure safe operation of emergency vehicles on the road.
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http://dx.doi.org/10.1016/j.aap.2023.107217 | DOI Listing |
ACS Appl Mater Interfaces
January 2025
School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.
In recent years, aqueous zinc-ion batteries (ZIBs) have shown considerable promise in the energy storage sector, attributed to their inherent high safety and cost-effectiveness. ZnVO(OH)·2HO (ZVO) has emerged as a promising candidate for Zn storage in recent years, owing to its exceptional structural stability that endows it with an excellent cycle life. However, an unsatisfactory rate performance is a limiting factor for its development in ZIBs.
View Article and Find Full Text PDFAdeno-associated viruses (AAVs) have emerged as the foremost gene therapy delivery vehicles due to their versatility, durability, and safety profile. Here we demonstrate extensive chimerism, manifesting as pervasive barcode swapping, among complex AAV libraries that are packaged as a pool. The observed chimerism is length- and homology-dependent but capsid-independent, in some cases affecting the majority of packaged AAV genomes.
View Article and Find Full Text PDFBackground: Targeting glutamine metabolism has emerged as a promising strategy in cancer therapy. However, several barriers, such as anti-tumor efficacy, drug toxicity, and safety, remain to be overcome to achieve clinical utility. Prior preclinical studies had generated encouraging data showing promises of cancer metabolism targeting drugs, although most were performed on immune-deficient murine models.
View Article and Find Full Text PDFRev Cardiovasc Med
January 2025
Department of Anesthesiology, Intensive Care Medicine, Emergency Medicine, Pain and Palliative Therapy, Asklepios Klinikum Harburg, 21075 Hamburg, Germany.
Out-of-hospital cardiac arrest (OHCA) is a leading cause of death worldwide, with a low survival rate of around 7% globally. Key factors for improving survival include witnessed arrest, bystander cardiopulmonary resuscitation (CPR), and early defibrillation. Despite guidelines advocating for the "chain of survival", bystander CPR and defibrillation rates remain suboptimal.
View Article and Find Full Text PDFLight Sci Appl
January 2025
National Research Center for High-Efficiency Grinding, College of Mechanical and Vehicle Engineering, Hunan University, 410082, Changsha, China.
Accurately and swiftly characterizing the state of polarization (SoP) of complex structured light is crucial in the realms of classical and quantum optics. Conventional strategies for detecting SoP, which typically involves a sequence of cascaded optical elements, are bulky, complex, and run counter to miniaturization and integration. While metasurface-enabled polarimetry has emerged to overcome these limitations, its functionality predominantly remains confined to identifying SoP within the standard Poincaré sphere framework.
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