AI Article Synopsis
- Benign spinal intradural tumors, although rare, include types like low-grade astrocytomas and ependymomas that occur within the spinal cord, as well as meningiomas and schwannomas that are found outside the cord.
- The impact of these tumors on neural tissue can vary, often causing pressure and, in cases of infiltrative tumors, direct involvement with nerve cells.
- Treatment primarily focuses on maximal safe surgical resection, with a greater chance of success in extramedullary tumors, while well-planned surgeries can also effectively address many intramedullary tumors, emphasizing functional recovery over traditional outcome measures like survival rates.
Article Abstract
Benign spinal intradural tumors are relatively rare and include intramedullary tumors with a favorable histology such as low-grade astrocytomas and ependymomas, as well as intradural extramedullary tumors such as meningiomas and schwannomas. The effect on the neural tissue is usually a combination of mass effect and neuronal involvement in cases of infiltrative tumors. The new understanding of molecular profiling of different tumors allowed us to better define central nervous system tumors and tailor treatment accordingly. The mainstay of management of many intradural spinal tumors is maximal safe surgical resection. This goal is more achievable with intradural extramedullary tumors; yet, with a meticulous surgical approach, many of the intramedullary tumors are amenable for safe gross-total or near-total resection. The nature of these tumors is benign; hence, a different way to measure outcome success is pursued and usually depends on functional rather than oncological or survival outcomes.
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| http://dx.doi.org/10.1007/978-3-031-23705-8_23 | DOI Listing |
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