AI Article Synopsis
- * Maternal obesity affects oocyte quality, resulting in higher chances of chromosomal abnormalities and reduced embryonic development, which can further decrease fertility.
- * The review examines how maternal obesity contributes to pregnancy complications and suggests strategies to mitigate its negative effects on female fertility.
Article Abstract
Currently, obesity has achieved epidemic levels in reproductive-aged women with a myriad of consequences. Obesity is susceptible to several reproductive complications that eventually affect fertility rates. These complications originate from the deteriorated quality of oocytes from mothers with obesity, which increases the probability of chromosomal aneuploidy, elevated reactive oxygen species production, compromised embryonic developmental competency, and eventually reduced fertility. Maternal obesity is linked to pregnancy complications such as implantation error, abortion, miscarriage, and early pregnancy loss. This review highlights the adverse effects of maternal obesity on female fertility, with a focus on the mechanistic link between maternal obesity and oocyte quality and discusses possible measures to reduce its associated risks.
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| http://dx.doi.org/10.1111/obr.13603 | DOI Listing |
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