AI Article Synopsis

  • The study reports on a new urethroplasty technique using a spiral preputial graft for treating panurethral stricture disease, assessed over a 12-month period.
  • Among the 20 patients treated, complications were relatively low, with most being mild to moderate according to the Clavien-Dindo classification, and the majority did not experience recurrence of the stricture.
  • Results showed a significant improvement in urinary flow rates post-surgery, suggesting this technique could be a safe and effective alternative to existing surgical options.

Article Abstract

Purpose: To report the 12-month results of a novel urethroplasty technique relying on a spiral preputial graft for panurethral stricture disease.

Materials And Methods: Twenty consecutive patients were treated between May and October 2021 at our center. A spiral preputial mucocutaneous graft is a foreskin-based graft, developed from a 5-cm-wide preputial skin, which is harvested using a helicoidal shape and can reach up to 20 cm in length. Stricture characteristics were assessed through preoperative retrograde and voiding cystourethrogram and maximum uroflowmetry data (Qmax). Complications were collected up to 30 days after surgery and graded using the Clavien-Dindo (C-D) classification. The patients were followed up to 12 months.

Results: Preoperative median Qmax was 6.5 ml/s [interquartile range (IQR): 4.0-8.7]. After a median follow-up of 12 months (IQR 12-13), six patients experienced at least one complication. Of them, two patients had grade 2 C-D complications, while only one developed a grade 3a C-D complication. The median postoperative Qmax was 16 ml/s (IQR: 13-18). Only one patient had early urethral stricture recurrence treated with dilatation after catheter removal. At one-year follow-up, no other patients had urethral stricture recurrence with an overall median Qmax of 15.1 ml/s (IQR 13.5-16.4).

Conclusions: Our novel single-stage spiral preputial graft urethroplasty for panurethral stricture treatment appears to be safe and could be used as a valid alternative to two-stage procedures or even to single-stage buccal mucosa graft augmentation.

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Source
http://dx.doi.org/10.1007/s00345-023-04514-9DOI Listing

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