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Partially hydrolyzed guar gum suppresses the progression of pulmonary arterial hypertension in a SU5416/hypoxia rat model. | LitMetric

AI Article Synopsis

  • - The study examined how partially hydrolyzed guar gum (PHGG) impacts pulmonary arterial hypertension in a rat model induced by SU5416 and hypoxia.
  • - Results showed that treating the rats with PHGG reduced the progression of pulmonary hypertension and changes in blood vessel structure.
  • - The treatment also led to significant changes in the composition of gut microbiota, suggesting a link between gut health and pulmonary conditions.

Article Abstract

This study investigated the effects of partially hydrolyzed guar gum (PHGG) on the development of pulmonary arterial hypertension using a SU5416/hypoxia rat model. Our results demonstrated that PHGG treatment suppressed the development of pulmonary hypertension and vascular remodeling with an altered gut microbiota composition.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336776PMC
http://dx.doi.org/10.1002/pul2.12266DOI Listing

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