Robust Vector BOTDA Signal Processing with Probabilistic Machine Learning.

Sensors (Basel)

National Energy Technology Laboratory, 626 Cochrans Mill Road, Pittsburgh, PA 15236, USA.

Published: June 2023

This paper presents a novel probabilistic machine learning (PML) framework to estimate the Brillouin frequency shift (BFS) from both Brillouin gain and phase spectra of a vector Brillouin optical time-domain analysis (VBOTDA). The PML framework is used to predict the Brillouin frequency shift (BFS) along the fiber and to assess its predictive uncertainty. We compare the predictions obtained from the proposed PML model with a conventional curve fitting method and evaluate the BFS uncertainty and data processing time for both methods. The proposed method is demonstrated using two BOTDA systems: (i) a BOTDA system with a 10 km sensing fiber and (ii) a vector BOTDA with a 25 km sensing fiber. The PML framework provides a pathway to enhance the VBOTDA system performance.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347185PMC
http://dx.doi.org/10.3390/s23136064DOI Listing

Publication Analysis

Top Keywords

pml framework
12
vector botda
8
probabilistic machine
8
machine learning
8
brillouin frequency
8
frequency shift
8
shift bfs
8
sensing fiber
8
robust vector
4
botda
4

Similar Publications

The 2020 mass mortality of 350 African elephants (Loxodonta africana) in Botswana sparked global concern, with cyanotoxins in watering holes (pans) being a suspected cause, though evidence remains inconclusive. Combining remote sensing and spatial analysis, we examined the relationship between the ecohydrology of ∼3000 pans and the locations of deceased elephants. Our analysis revealed a significant difference in the spatial distribution of fresh versus decayed carcasses (p < 0.

View Article and Find Full Text PDF

Heterochromatin is a pivotal element in the functional organization of genomes. In our study, we delve into the heterochromatin pattern of association by the PML (promyelocytic leukemia) protein. By using PML chromatin immunoprecipitation and sequencing data and comparing computational methodologies to depict PML chromatin association, we describe PML-associated domains or PADs as large heterochromatic regions that exhibit similar genomic features across cancer cell lines.

View Article and Find Full Text PDF

Blood DNA methylomic signatures associated with CSF biomarkers of Alzheimer's disease in the EMIF-AD study.

Alzheimers Dement

October 2024

Department of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, Devon, UK.

Article Synopsis
  • The study examined DNA methylation patterns in blood samples related to 15 key biomarkers of Alzheimer's disease, focusing on neuroinflammation and neurodegeneration effects.
  • Using 885 samples from the EMIF-AD study, researchers identified significant differential methylation connected to CSF levels of YKL-40 and neurofilament light chain (NfL).
  • Findings suggest a link between YKL-40 DNA methylation and genetic variants, with implications for understanding how DNA methylation influences protein levels relevant to Alzheimer's disease.
View Article and Find Full Text PDF

CD19-directed chimeric antigen receptor T-cell (CAR T) therapies, including axicabtagene ciloleucel (axi-cel), tisagenlecleucel (tisa-cel), and lisocabtagene maraleucel (liso-cel), have transformed the treatment landscape for B-cell non-Hodgkin lymphoma, showcasing significant efficacy but also highlighting toxicity risks such as cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS). The US Food and Drug Administration has mandated patients remain close to the treatment center for 4 weeks as part of a Risk Evaluation and Mitigation Strategy to monitor and manage these toxicities, which, although cautious, may add to cost of care, be burdensome for patients and their families, and present challenges related to patient access and socioeconomic disparities. This retrospective study across 9 centers involving 475 patients infused with axi-cel, tisa-cel, and liso-cel from 2018 to 2023 aimed to assess CRS and ICANS onset and duration, as well as causes of nonrelapse mortality (NRM) in real-world CAR T recipients.

View Article and Find Full Text PDF

Partial multilabel learning (PML) addresses the issue of noisy supervision, which contains an overcomplete set of candidate labels for each instance with only a valid subset of training data. Using label enhancement techniques, researchers have computed the probability of a label being ground truth. However, enhancing labels in the noisy label space makes it impossible for the existing partial multilabel label enhancement methods to achieve satisfactory results.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!