Anthocyanins are flavonoid compounds that are abundantly present in fruits and vegetables. These compounds contribute to the color of these foods and offer various health benefits to consumers due to their biological properties. There are more than 1000 types of anthocyanins in nature, all derived from 27 anthocyanidin aglycones that have different glycosylations and acylations. Malvidin is one of the most well-known anthocyanidins. Several studies, including those conducted on cell lines, animals, and humans, have suggested that malvidin and its glycosides possess anti-carcinogenic, diabetes-control, cardiovascular-disease-prevention, and brain-function-improvement properties. These health benefits are primarily attributed to their antioxidant and anti-inflammatory effects, which are influenced by the molecular mechanisms related to the expression and modulation of critical genes. In this article, we review the available information on the biological activity of malvidin and its glycosides concerning their health-promoting effects.
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http://dx.doi.org/10.3390/nu15133016 | DOI Listing |
Genes (Basel)
November 2024
Institute of Flowers, Liaoning Academy of Agricultural Sciences, Shenyang 110161, China.
: is a perennial herb of the Verbenaceae family, known for its medicinal properties, wide adaptability, and high resistance. : This research investigated the metabolic pathways of flower color change by combining transcriptome and metabolomics analyses. : In purple flowers and white variants, a total of 118 differentially accumulated metabolites (DAMs), including 20 anthocyanins, and 7627 differentially expressed genes (DEGs) were found.
View Article and Find Full Text PDFInt J Mol Sci
November 2024
Department of Food and Nutrition, College of BioNano Technology, Gachon University, Seongnam 13120, Republic of Korea.
Parkinson's disease (PD) is a widespread age-related neurodegenerative disorder characterized by the presence of an aggregated protein, α-synuclein (α-syn), which is encoded by the gene and localized to presynaptic terminals in a normal human brain. The α-syn aggregation is induced by the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mitochondrial neurotoxin and is therefore used to mimic PD-like pathology in various in vitro and in vivo models. However, in vitro PD-like pathology using α-syn and MPTP in human microglial cells has not yet been reported.
View Article and Find Full Text PDFFood Chem
March 2025
Wine Science Programme, School of Chemical Sciences, The University of Auckland | Waipapa Taumata Rau, 23 Symonds Street, Auckland 1010, New Zealand. Electronic address:
A total of 116 New Zealand Pinot Noir wines from Central Otago (CO), Marlborough (MLB), and Martinborough (MTB) were analysed for colour, monomeric and total phenolics, antioxidant capacity, and tannins using colourimetric and HPLC methods. Correlations among chemical compositions and analytical techniques were examined. Additionally, a sensory study assessed wine colour and five mouthfeel attributes.
View Article and Find Full Text PDFFood Res Int
November 2024
School of Life Sciences, Yantai University, Yantai, Shandong 264005, China. Electronic address:
Monomeric flavan-3-ols are important copigments in red wines, due to their superior copigmentation ability and high concentration. In this work, a systematic study was conducted on the copigmentation effects of eight common monomeric flavan-3-ols with malvidin-3-O-glucoside, using experimental and theoretical methods. The results revealed that the addition of a hydroxy group to the B ring and the attachment of a galloyl group at the 3-O position of monomeric flavan-3-ols both contributed to enhance copigmentation, with the latter exerting a more pronounced effect.
View Article and Find Full Text PDFMolecules
November 2024
School of Bioengineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China.
Acetaldehyde is a key carbonyl by-product during red wine alcoholic fermentation; it is reactive and takes part in certain reactions involving anthocyanin. The aim of this study was to investigate the influence of SO and condensed tannin on the acetaldehyde accumulation of () during alcoholic fermentation and the ripple effect on wine anthocyanin. In this study, six sets of Cabernet Sauvignon alcoholic fermentation with two different sulfur levels (HS and LS) were carried out by adding exogenous condensed tannins before fermentation (T0) in the acetaldehyde rise period (TA) of and at the end of fermentation (TE), separately.
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