Herein, we have designed and synthesized a novel type-I photosensitizer (PhPA) Rh-catalyzed oxidative cyclization of diacetoxyterephthalamide with alkynes. The photoelectric properties, photosensitivity and photodegradation process of PhPA have been systematically investigated. The remarkable fluorescence quenching effect ( < 0.01) of PhPA suggests that the intersystem crossing from the singlet excited state to the reactive triplet state is enhanced by the enlarged conjugated backbone. Additionally, the ability of superoxide radical (O˙) generation was confirmed by electron paramagnetic resonance spectroscopy. Finally, the mechanism of PhPA photo-oxidative degradation the structure of two metabolites is proposed.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334370 | PMC |
| http://dx.doi.org/10.1039/d3na00341h | DOI Listing |
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