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Inducing Neural Regeneration from Glia Using Proneural bHLH Transcription Factors. | LitMetric

Inducing Neural Regeneration from Glia Using Proneural bHLH Transcription Factors.

Adv Exp Med Biol

Department of Biological Structure, University of Washington, Seattle, WA, USA.

Published: July 2023

AI Article Synopsis

Article Abstract

Endogenous regeneration strategies to replace lost neurons hold great promise for treating neurodegenerative disorders. In the majority of cases, neural regeneration is induced by converting resident glial cells into neurogenic precursors. This review will outline how proneural bHLH transcription factors can be used to reprogram glia in the brain and retina into a source for new neurons.

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-3-031-27681-1_84DOI Listing

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