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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337140PMC
http://dx.doi.org/10.1186/s12929-023-00948-wDOI Listing

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Article Synopsis
  • A study was conducted to investigate similarities and differences in protein expressions between psoriasis (PS) and atopic dermatitis (AD), using high-throughput mass spectrometry on skin samples from affected patients and healthy controls.
  • The analysis revealed a significant overlap in proteomic profiles of PS and AD, indicating they share common pathogenesis mechanisms, while both differed from healthy skin.
  • Notably, periostin (POSTN) was found to be highly expressed in AD but very low or absent in PS, suggesting its potential as a biomarker to distinguish between the two conditions.
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