Hierarchical Structuration in Protocellular System.

Small Methods

Key Laboratory of Biomedical Engineering of Ministry of Education, Zhejiang Provincial Key Laboratory of Cardio-Cerebral Vascular Detection Technology and Medicinal Effectiveness Appraisal, Department of Biomedical Engineering, Zhejiang University, Hangzhou, 310027, China.

Published: December 2023

AI Article Synopsis

  • Spatial control is essential for the complexity of living cells and is important for constructing advanced artificial living systems that can behave collectively.* -
  • The authors review recent developments in achieving spatial control within single protocells and among multiple protocells, highlighting its significance for studying complex biological systems.* -
  • The findings may contribute to creating functional microreactors capable of programmable biomacromolecular release and hybrid systems that combine protocells with biological cells.*

Article Abstract

Spatial control is one of the ubiquitous features in biological systems and the key to the functional complexity of living cells. The strategies to achieve such precise spatial control in protocellular systems are crucial to constructing complex artificial living systems with functional collective behavior. Herein, the authors review recent advances in the spatial control within a single protocell or between different protocells and discuss how such hierarchical structured protocellular system can be used to understand complex living systems or to advance the development of functional microreactors with the programmable release of various biomacromolecular payloads, or smart protocell-biological cell hybrid system.

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Source
http://dx.doi.org/10.1002/smtd.202300422DOI Listing

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