AI Article Synopsis
- The study aimed to review the prevalence and risk factors of frailty in patients with chronic obstructive pulmonary disease (COPD) using systematic methods and meta-analysis of published studies up to September 2022.
- The analysis included 38 articles, revealing that approximately 36% of COPD patients were frail, while 43% were classified as pre-frail, with age and COPD assessment test scores increasing the likelihood of frailty.
- Conversely, higher education and income levels were associated with a reduced risk of frailty, highlighting various influencing factors related to this condition in COPD patients.
Article Abstract
Objective: To systematically review the prevalence and risk factors for frailty in patients with chronic obstructive pulmonary disease (COPD).
Methods: A systematic review and meta-analysis were conducted, and a search of the PubMed, Embase and Web of Science databases was carried out to collect Chinese and English studies on frailty and COPD published up to September 5, 2022.
Results: A total of 38 articles were included for the quantitative analysis after the collected literature was either included or omitted based on pertinent criteria. The results indicated that the estimated overall pooled prevalence of frailty was 36% (95% confidence interval [CI] = 31-41%), and the estimated pre-frailty was 43% (95% CI = 37-49%). A higher age (odds ratio [OR] = 1.04; 95% CI = 1.01-1.06) and higher COPD assessment test (CAT) score (OR = 1.19; 95% CI = 1.12-1.27) were associated with a significantly increased likelihood of frailty in patients with COPD. However, a higher educational attainment (OR = 0.55; 95% CI = 0.43-0.69) and higher income (OR = 0.63; 95% CI = 0.45-0.88) were associated with a significantly reduced risk of frailty in patients with COPD. A total of 17 other risk factors for frailty were identified via qualitative synthesis.
Conclusion: The incidence of frailty in patients with COPD is high, and there are many influencing factors.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447286 | PMC |
| http://dx.doi.org/10.1007/s41999-023-00800-2 | DOI Listing |
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