AI Article Synopsis
- - A new strain of porcine reproductive and respiratory syndrome virus (PRRSV), called YC-2020, was found in a pig farm in Yuncheng, Shanxi Province, China.
- - Genetic analysis revealed that YC-2020 shares similarities with both NADC34-like PRRSV strains and NADC30-like strains, indicating that it likely resulted from recombination between different virus lineages.
- - Infected piglets showed mild symptoms but severe lung tissue damage, highlighting unique genetic and harmful characteristics of the YC-2020 strain.
Article Abstract
In this study, an NADC34-like strain of porcine reproductive and respiratory syndrome virus (PRRSV), YC-2020, was isolated from a pig farm in Yuncheng, Shanxi Province, China. Phylogenetic and molecular evolutionary analysis showed that the genome sequence of YC-2020 was very similar to those of NADC34-like PRRSV strains in the ORF2-7 region. However, it was more closely related to NADC30-like PRRSV and highly pathogenic (HP) PRRSV in the NSP2 and NSP3-9 coding regions, respectively, suggesting that recombination had occurred between viruses belonging to lineages 1 and 8. Piglets infected with YC-2020 exhibited mild clinical signs, but they had severe histopathological lesions in their lungs. These findings reveal novel genetic and pathogenic features of this isolate.
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| http://dx.doi.org/10.1007/s00705-023-05822-6 | DOI Listing |
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