AI Article Synopsis
- Spindle cell carcinoma (SpCC) is a rare type of cancer that makes up less than 3% of head and neck squamous cell carcinomas and mostly occurs in older adults.
- SpCC is typically associated with smoking and alcohol use but this case involved a young patient with xeroderma pigmentosum who was a nonsmoker and did not drink.
- The tumor originated in the right orbit and affected the entire right side of the face, and the patient underwent surgical excision with the diagnosis confirmed through postoperative histopathological analysis.
Article Abstract
Spindle cell carcinoma (SpCC), also referred to as sarcomatoid carcinoma, makes up less than 3% of all head and neck squamous cell carcinomas (SCCs). It is an uncommon and unusual biphasic malignant tumor primarily affecting the upper aero-digestive tract. SpCC consists of spindled or pleomorphic tumor cells. Mostly, these tumors are seen in the fifth or sixth decades of life and are strongly associated with smoking and alcohol. We hereby report an infrequently encountered case of SpCC in a patient with xeroderma pigmentosum (XP), who was young, nonsmoker, and did not consume alcohol. The mass arose from the right orbit and involved the entire right face. The postoperative histopathological report showed SpCC. Surgical excision of the mass was performed. We aimed to add to the prevailing literature by reporting this case.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332866 | PMC |
| http://dx.doi.org/10.14740/jmc4110 | DOI Listing |
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