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Background: Borderline acetabular dysplasia is commonly radiographically defined as a lateral center-edge angle (LCEA) of 20° to 25°. While the variability of plain radiographic assessment of this population has been reported, an understanding of the variability of 3-dimensional (3D) hip morphology remains to be better defined.
Purpose: To investigate the variability of 3D hip morphology present on low-dose computed tomography (CT) in the setting of symptomatic borderline acetabular dysplasia and to determine if plain radiographic parameters correlate with 3D coverage.
Study Design: Cohort study (diagnosis); Level of evidence, 2.
Methods: A total of 70 consecutive hips with borderline acetabular dysplasia undergoing hip preservation surgery were included in the current study. Plain radiographic evaluation included LCEA, acetabular inclination, anterior center-edge angle (ACEA), anterior wall index (AWI), posterior wall index (PWI), and alpha angles on anteroposterior, 45° Dunn, and frog-leg views. All patients underwent low-dose pelvic CT for preoperative planning, which allowed detailed characterization of 3D morphology relative to normative data. Acetabular morphology was assessed with radial acetabular coverage (RAC) calculated according to standardized clockface positions from 8:00 (posterior) to 4:00 (anterior). Coverages at 10:00, 12:00, and 2:00 were classified as normal, undercoverage, or overcoverage relative to 1 SD from the mean of normative RAC values. Femoral morphology was assessed with femoral version, alpha angle (measured at 1:00 increments), and maximum alpha angle. Correlation was assessed with the Pearson correlation coefficient ().
Results: Lateral coverage (12:00 RAC) was deficient in 74.1% of hips with borderline dysplasia. Anterior coverage (2:00 RAC) was highly variable, with 17.1% undercoverage, 72.9% normal, and 10.0% overcoverage. Posterior coverage (10:00 RAC) was also highly variable, with 30.0% undercoverage, 62.9% normal, and 7.1% overcoverage. The 3 most common patterns of coverage were isolated lateral undercoverage (31.4%), normal coverage (18.6%), and combined lateral and posterior undercoverage (17.1%). The mean femoral version was 19.7°± 10.6° (range, -4° to 59°), with 47.1% of hips having increased femoral version (>20°). The mean maximum alpha angle was 57.2° (range, 43°-81°), with 48.6% of hips having an alpha angle ≥ 55°. The ACEA and AWI were poorly correlated with radial anterior coverage ( = 0.059 and 0.311, respectively), while the PWI was strongly correlated with radial posterior coverage ( = 0.774).
Conclusion: Patients with borderline acetabular dysplasia demonstrate highly variable 3D deformities, including anterior, lateral, and posterior acetabular coverage; femoral version; and alpha angle. Plain radiographic assessments of anterior coverage are poorly correlated with anterior 3D coverage on low-dose CT.
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http://dx.doi.org/10.1177/03635465231184395 | DOI Listing |
J Ultrason
December 2024
Paediatrics, Azienda Ospedaliera Sant'Andrea, Roma, Italy.
Aim: Aiming to offer a diagnostic tool to aid examiners with correct hip typing and decision-making about patient management, members of the Board of the International Interdisciplinary Consensus Committee on DDH Evaluation (ICODE - https://www.icode.expert), introduced the cross-platform mobile application (Android and iOS) called "ICODE Hip US Calculator".
View Article and Find Full Text PDFBiophys J
December 2024
Institute for Integrated Radiation and Nuclear Science, Kyoto University, Kumatori, Sennan-gun, Osaka 590-0494 Japan. Electronic address:
Intrinsically disordered proteins (IDPs) show structural changes stimulated by changes in external conditions. This study aims to reveal the temperature dependence of the structure and dynamics of the intrinsically disordered region of Hef, one of the typical IDPs, using an integrative approach. Small-angle X-ray scattering (SAXS) and circular dichroism (CD) studies revealed that the radius of gyration and ellipticity at 222 nm remained constant up to 313-323 K, followed by a decline above this temperature range.
View Article and Find Full Text PDFBMC Oral Health
December 2024
Faculty of Dentistry, Department of Orthodontics, Ondokuz Mayıs University, Atakum, Samsun, 55139, Turkey.
Background: This retrospective study aimed to investigate the relationships between the radiographic features of impacted maxillary canines (IMCs) and traction duration and the factors affecting treatment success.
Methods: Pre-treatment panoramic radiographs and patient records of 121 consecutive patients with IMCs were analyzed. The measurements included the angle of the IMC with the midline (α-angle), the horizontal position of the IMC relative to the adjacent teeth (S-Sector), the distance from the IMC to the occlusal plane (d-distance), the apex position of the IMC (A), and the vertical height of the IMC relative to the adjacent lateral tooth (V).
Biochemistry
December 2024
Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States.
The effects of guanidinium hydrochloride (GdmCl) on two intrinsically disordered proteins (IDPs) are investigated using simulations of the self-organized polymer-IDP (SOP-IDP) model. The impact of GdmCl is taken into account using the molecular transfer model (MTM). We show that due to the dramatic reduction in the stiffness of the highly charged Prothymosin-α (ProTα) with increasing concentration of GdmCl ([GdmCl]), the radius of gyration () decreases sharply until about 1.
View Article and Find Full Text PDFPhys Rev Lett
December 2024
Center for Theoretical Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Energy correlators provide a powerful observable to study fragmentation dynamics in QCD. We demonstrate that the leading nonperturbative corrections for projected N-point energy correlators are described by the same universal parameter for any N, which has already been determined from other event shape fits. Including renormalon-free nonperturbative corrections substantially improves theoretical predictions of energy correlators, notably the transition into the confining region at small angles.
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