Introduction: Road traffic injuries are a significant issue for society in the twenty-first century, but public health experts frequently ignore them despite the fact that massive and coor-dinated efforts are required for their effective and long-term prevention. Human factors and poor driving performance are the most significant contributors to car accidents globally, as shown by a series of studies exploring the causes of traffic road accidents. Since road safety is a key concern in developing countries, our research focuses on the car driver behavioral risk factors in the Republic of Moldova.
Material And Methods: A cross-sectional quantitative descriptive using a questionnaire was applied online via a Google form document among car drivers, between January-March 2022. Microsoft Excel was used for the statistical analyses.
Results: The questionnaire was completed by 257 respondents above 18 years, of which 61.9% were female and 38.1% were male, mostly with a category B license (73.5%) and majority from urban area (87.5%). More than half (55.6%) mention that drove a car daily and 30% of them have a drive experience of more than ten years. Respondents express great concern (71.2%) about the issue of traffic accidents, and 76.3% think that unsafe roads are a key contributing factor. At least once being involved as a driver in road accidents where medical care was needed was mentioned by 2.7% of respondents.
Conclusions: Educational programs and awareness campaigns about road safety among drivers and other vulnerable road users should be systematically organized.
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http://dx.doi.org/10.38045/ohrm.2023.2.04 | DOI Listing |
Int J Neuropsychopharmacol
January 2025
Center for Drug Clinical Research, Shanghai University of Traditional Chinese Medicine, No.1200 Cailun Road, Shanghai 201203, China.
Objective: This study aims to quantitatively evaluate the efficacy and safety of various treatment regimens for treatment-resistant depression (TRD) across oral, intravenous, and intranasal routes to inform clinical guidelines.
Methods: A systematic review identified randomized controlled trials on TRD, with efficacy measured by changes in the Montgomery-Åsberg Depression Rating Scale (MADRS). We developed pharmacodynamic and covariate models for different administration routes, using Monte Carlo simulations to estimate efficacy distribution.
Viruses
January 2025
Key Laboratory of Extreme Environmental Microbial Resources and Engineering, Lanzhou 730000, China.
Recent decades have seen growing attention on viruses in the environment and their potential impacts as a result of global epidemics. Due to the diversity of viral species along with the complexity of environmental and host factors, virus extraction and detection methods have become key for the study of virus ecology. This review systematically summarises the methods for extracting and detecting pathogens from different environmental samples (e.
View Article and Find Full Text PDFPharmaceutics
December 2024
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM's NMIMS, V.L. Mehta Road, Vile Parle (W), Mumbai 400056, Maharashtra, India.
Liposome-based drug delivery technologies have showed potential in enhancing medication safety and efficacy. Innovative drug loading and release mechanisms highlighted in this review of next-generation liposomal formulations. Due to poor drug release kinetics and loading capacity, conventional liposomes have limited clinical use.
View Article and Find Full Text PDFNutrients
January 2025
Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, No. 76, Yanta West Road, Xi'an 710061, China.
As a widely consumed, nutritious, and affordable food, eggs and their derivatives' impacts on obesity remain inconclusive. In this study, we aimed to determine the association between egg and egg-derived cholesterol consumption, and their change trajectories, with obesity among Chinese adults. : Longitudinal data collected by the China Health and Nutrition Survey from 1997 to 2015 were analyzed.
View Article and Find Full Text PDFPathogens
January 2025
Plant Omics Laboratory, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Robert Sobukwe Road, Bellville 7535, South Africa.
head blight (FHB) is a major disease affecting wheat production worldwide, caused by multiple species. In this study, seven strains were isolated from wheat fields across the Western Cape region of South Africa and identified through phylogenetic analysis. The strains were classified into three species complexes: the species complex (FGSC), species complex (FIESC), and species complex (FTSC).
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