Regulatory and ethical considerations mandate that minorities affected by health disparities be included in research. Despite concerns about clinical outcomes for patients with obesity, clinical trials have reported few data about participation of and outcomes for such patients. This article examines the lack of body size diversity in clinical research participants and reviews the evidence and ethical arguments for including larger-bodied patients. Drawing on examples of improved gender diversification of trial participants, this article suggests that similar benefits would be likely from inclusion of body diversity.
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http://dx.doi.org/10.1001/amajethics.2023.517 | DOI Listing |
J Anim Breed Genet
January 2025
Department of Animal Biosciences, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Swedish Warmblood horses (SWB) are bred for show jumping and/or dressage with young horse test scores as indicator traits. This study aimed to investigate possible candidate genes and regions of importance for evaluated and linearly scored young horse test traits. A single-step genome-wide association study (ssGWAS) was done using the BLUPF90 suite of programs for factors scores from factor analysis of traits assessed at young horse tests together with height at withers.
View Article and Find Full Text PDFAnn Otol Rhinol Laryngol
January 2025
School of Clinical Medicine, Women's Health Paediatrics and Child Health, University of New South Wales, Sydney, NSW, Australia.
Objectives: The prevalence of obstructive sleep apnea (OSA) is known to be higher in children with Down syndrome (DS) than the general pediatric population, with lower rates of surgical cure. This study aims to determine the prevalence and predictors of OSA and evaluate the outcomes of surgical intervention for OSA in a cohort of Australian children with DS.
Methodology: A retrospective chart review was conducted on 156 patients with DS from 0 to 18 years who had undergone overnight, attended polysomnography (PSG) at Sydney Children's Hospital from January 2010 to July 2023.
J Dent Res
January 2025
Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Missing teeth have been linked to incident cardiovascular disease, diabetes, and all-cause mortality. Our previous study revealed that signs of oral infections and inflammatory conditions (i.e.
View Article and Find Full Text PDFEur J Sport Sci
February 2025
Sports Performance Research Institute New Zealand, Auckland University of Technology, Auckland, New Zealand.
The aim of this study was to quantify the training effects of wearing calf-loaded wearable resistance (WR) during a netball specific warm-up in female netball athletes. Twenty-nine high school female netball athletes were matched for change of direction (COD) speed and randomly allocated to either WR training or an unloaded group. Both groups performed the same warm-up two times per week for 6 weeks, with the WR group wearing 1%-1.
View Article and Find Full Text PDFSci Total Environ
January 2025
Ulm University, Institute of Evolutionary Ecology and Conservation Genomics, Albert-Einstein-Allee 11, 89081 Ulm, Germany. Electronic address:
Agricultural management significantly affects insects, especially pollinators, which are crucial for crop pollination and biodiversity. In agricultural landscapes, various factors spanning different spatial scales are known to affect pollinator health, which, in turn, can influence pollination services. However, the importance of these factors in driving the health and performance of different pollinator groups remains unclear.
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