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| http://dx.doi.org/10.1111/bju.16101 | DOI Listing |
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HIV interventions across the care continuum for adolescents in high-burden countries: a systematic review and meta-analysis.
EClinicalMedicine
December 2024
University of North Carolina Project-China, Guangzhou, China.
Background: Adolescents (10-19 years old) have poor outcomes across the prevention-to-treatment HIV care continuum, leading to significant mortality and morbidity. We conducted a systematic review and meta-analysis of interventions that documented HIV outcomes among adolescents in HIV high-burden countries.
Methods: We searched PubMed, EMBASE, Scopus, and the Cochrane Library for studies published between January 2015 and September 2024, assessing at least one HIV outcome along the prevention-to-care cascade, including PrEP uptake, HIV testing, awareness of HIV infections, ARV adherence, retention, and virological suppression.
To determine if the use of theory, data and end-user perspectives to guide an adaptation of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) yields better outcomes and improves the "fit" of TranS-C to community mental health centers (CMHCs), relative to the standard version. Ten counties in California were cluster-randomized by county to Adapted or Standard TranS-C. Within each county, adults who exhibited sleep and circadian dysfunction and serious mental illness (SMI) were randomized to immediate TranS-C or Usual Care followed by Delayed Treatment with TranS-C (UC-DT).
View Article and Find Full Text PDFNovel multiplexed spatial proteomics imaging platforms expose the spatial architecture of cells in the tumor microenvironment (TME). The diverse cell population in the TME, including its spatial context, has been shown to have important clinical implications, correlating with disease prognosis and treatment response. The accelerating implementation of spatial proteomic technologies motivates new statistical models to test if cell-level images associate with patient-level endpoints.
View Article and Find Full Text PDFA Ge.F.I. Collaborative Study: Evaluating Reproducibility and Accuracy of a DNA-Methylation-Based Age-Predictive Assay for Routine Implementation in Forensic Casework.
Electrophoresis
January 2025
Forensic Sciences Laboratory, Section of Legal Medicine, Department of Medicine and Surgery, Santa Maria Hospital, University of Perugia, Terni, Italy.
The increasing interest in DNA methylation (DNAm) analysis within the forensic scientific community prompted a collaborative project by Ge.F.I.
View Article and Find Full Text PDFImplementing Team-Based Learning in a First-Year, Doctor of Physical Therapy Clinical Medicine Course.
J Phys Ther Educ
January 2025
Jeff Hartman is an assistant professor in the Doctor of Physical Therapy Program, Department of Family Medicine and Community Health at the University of Wisconsin School of Medicine and Public Health, 5110 Medical Sciences Center, 1300 University Ave. Madison, WI 53706 Please address all correspondence to Jeff Hartman.
Background And Purpose: Team-based learning (TBL) allows students to safely struggle with the complexity of clinical practice, yet there are few reports describing implementation in United States Doctor of Physical Therapy (DPT) education. The purpose of this paper is to report the implementation of TBL in a first-year clinical decision-making course within a DPT Program and compare the learning outcomes to a lecture-based teaching model.
Model/method Description And Evaluation: Team-based learning is an evidence-based, active learning technique whereby students complete clearly communicated, preclass assignments and come to class prepared to apply acquired knowledge and solve real-world scenarios in permanent, predetermined work teams.
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