Mitral regurgitation secondary to ischemic heart disease carries a significant mortality in the untreated patient. We report on 141 patients with mitral regurgitation secondary to ischemic heart disease who underwent complete coronary revascularization and correction of mitral regurgitation by either repair (101 patients) or replacement (40 patients). Good long- and short-term palliation was obtained. Left ventricular function (ejection fraction) and recent myocardial infarction were important preoperative determinants of outcome. Repair of the mitral apparatus rather than valve replacement was associated with better long- and short-term survival, especially in the patient with a low ejection fraction. The repaired valve is durable and repair minimizes the risks of thromboembolism, hemolysis, anticoagulation, and intracardiac infection associated with prosthetic valve replacement. Mitral valve repair was possible in 70% of the patients in this series. The benefit to the patient, especially the patient with compromised ventricular function, compensates the surgeon for any extra effort involved in conservation of the mitral apparatus.
Download full-text PDF |
Source |
---|
Acta Med Indones
October 2024
Department of Cardiology and Vascular Medicine Universitas Indonesia - Universitas Indonesia Hospital, Depok, Indonesia.
Functional mitral regurgitation is characterized by normal structures of the mitral valve and chordae tendinea, but the regurgitation occurs due to geometric changes in the left atrium and left ventricle. This condition can contribute to heart failure progression and lead to a poor prognosis. Functional mitral regurgitation is found in approximately one-third of patients with heart failure with a decreased ejection fraction.
View Article and Find Full Text PDFAnn Thorac Surg
January 2025
Department of Cardiac Surgery, University of Michigan, Ann Arbor, MI.
Background: The etiology of increased risk for reoperation after transcatheter aortic valve replacement (TAVR) versus prior surgical aortic valve replacement (SAVR) is poorly understood. This study evaluated the impact of concomitant mitral and tricuspid valve disease on associated risk of TAVR explant.
Methods: Patients undergoing aortic valve replacement after prior SAVR or TAVR were extracted from the Society of Thoracic Surgeons Adult Cardiac Surgery Database (2011-2021).
J Cardiovasc Magn Reson
January 2025
Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. Electronic address:
Background: Four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) shows promise for quantifying mitral regurgitation (MR) by allowing for direct regurgitant volume (RVol) measurement using a plane precisely placed at the MR jet. However, the ideal location of a measurement plane remains unclear. This study aims to systematically examine how varying measurement locations affect RVol quantification and determine the optimal location using the momentum conservation principle of a free jet.
View Article and Find Full Text PDFIndian Heart J
January 2025
Department of Cardiology, Chest Diseases Hospital, Kuwait. Electronic address:
Industry's influence on clinical trials is well known and extends to various aspects beyond funding, including industry-affiliated authors and industry-affiliated analysts. An area of potential concern is presentation of analyzed data that does not appear favorable to the desired study outcome. Such important data are at times not accorded prominence in discussion.
View Article and Find Full Text PDFComput Biol Med
January 2025
LaBS, Dipartimento di Chimica, Materiali e Ingegneria Chimica "Giulio Natta", Politecnico di Milano, Piazza Leonardo da Vinci 32, Milan, 20133, Italy. Electronic address:
In the context of dynamic image-based computational fluid dynamics (DIB-CFD) modeling of cardiac system, the role of sub-valvular apparatus (chordae tendineae and papillary muscles) and the effects of different mitral valve (MV) opening/closure dynamics, have not been systemically determined. To provide a partial filling of this gap, in this study we performed DIB-CFD numerical experiments in the left ventricle, left atrium and aortic root, with the aim of highlighting the influence on the numerical results of two specific modeling scenarios: (i) the presence of the sub-valvular apparatus, consisting of chordae tendineae and papillary muscles; (ii) different MV dynamics models accounting for different use of leaflet reconstruction from imaging. This is performed for one healthy subject and one patient with mitral valve regurgitation.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!