Two alternative anesthetic techniques for use during carotid endarterectomy were studied in a series of 424 procedures. A total of 248 were performed in patients under general anesthesia and 176 patients received regional block anesthesia. Perioperative instability of blood pressure was noted in 108 patients. Hypertension was noted in 17.7% of those under general anesthesia vs 20.5% of those under regional block anesthesia. Intravenous vasodilator agents were used for 19.62 hr (+/- 4.33) in the general anesthesia group vs 1.4 hr (+/- 0.44) in the regional block anesthesia group (p less than .02). Perioperative hypertension correlated best with uncontrolled preoperative hypertension. Under regional block anesthesia the incidence of shunting was 4.5%. The 1 month operative mortality for the entire carotid series was 1.2% (5/424). There were three stroke-related deaths. In addition, two nonfatal major strokes and two minor strokes occurred in patients who received general anesthesia vs one nonfatal major stroke in a patient who received regional block anesthesia.
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