Generalized keratosis pilaris induced by testosterone injections in a patient with CHARGE syndrome.

Dermatol Reports

Dermatology and Dermatologic Surgery Department, Prince Sultan Military Medical City, Riyadh.

Published: June 2023

AI Article Synopsis

  • - Keratosis pilaris (KP) is a skin condition marked by small, rough bumps around hair follicles, often accompanied by redness, and is quite common, particularly in kids and adolescents.
  • - It can affect up to 50% of healthy children and is even more prevalent in children with atopic dermatitis, generally becoming less common as people age.
  • - The report discusses a unique case involving a 13-year-old boy with CHARGE syndrome who developed widespread KP following testosterone injections, marking this as the first documented instance of this occurrence.

Article Abstract

Keratosis pilaris (KP) is a common disorder of follicular keratinization characterized by keratotic follicular papules with varying degrees of perifollicular erythema. Keratosis pilaris affects up to half of normal children and up to three-quarters of children with atopic dermatitis. KP is prominent during adolescence and less common in older people, but it may occur in children and adults of all ages. In this report, we describe the case of a 13-year-old boy known to have CHARGE syndrome who developed generalized keratosis pilaris after testosterone injections. To the best of our knowledge, this is the first reported case of generalized keratosis pilaris induced by testosterone injection.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327667PMC
http://dx.doi.org/10.4081/dr.2023.9661DOI Listing

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