The case report shares evidence for a better understanding of atrial standstill. This being a rare arrhythmogenic condition. This is a 46-year-old woman presented with multiple sites of arterial embolism, including lower extremity arteries, coronary artery, and cerebral artery. Unexpectedly, multiple arterial embolization in the patient was due to atrial standstill by transthoracic echocardiography and cardiac electrophysiological study. An additional family investigation revealed that the patient's brother and sister also suffered from this disease. In search of further understanding the case, we carried out the genetic testing of the family and a frame shift double-G insertion mutation at c.1567 in the gene was found in all the three individuals. The patient recovered well after anticoagulation therapy and left bundle branch area pacing. This report remarks on the importance of multiple sites of arterial embolism which should be wary of family atrial standstill.
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http://dx.doi.org/10.1177/2050313X231179810 | DOI Listing |
Kardiol Pol
January 2025
1st Department of Cardiology, Medical University of Silesia, Katowice, Poland, Centre of the European Reference Network for Rare, Low Prevalence or Complex Diseases of the Heart (ERN GUARD Heart).
Eur Heart J Case Rep
December 2024
Department of Cardiology, Hyogo Prefectural Awaji Medical Center, 1-1-137 Shioya, Sumoto 656-0021, Japan.
Background: Atrial standstill is characterized by the absence of atrial activity. We report a case of a patient with extensive atrial fibrosis who underwent electrophysiologic study (EPS) and electroanatomical mapping (EAM) to identify surviving atrial sites amenable for pacemaker lead implantation.
Case Summary: A 72-year-old man with persistent atrial fibrillation (AF) and atrial functional mitral regurgitation/tricuspid regurgitation (MR/TR) underwent a Cox-Maze surgery, mitral and tricuspid valve repair, and biatrial plication.
We present a case of HCN4 gene mutation presenting with atrial standstill and stroke in the young.
View Article and Find Full Text PDFJ Arrhythm
December 2024
Department of Cardiology and Clinical Examination, Faculty of Medicine Oita University Yufu Oita Japan.
Cureus
September 2024
Cardiothoracic Surgery, Munakata Suikokai General Hospital, Fukutsu, JPN.
We report a case of atrial functional tricuspid regurgitation with an atrial standstill in a 71-year-old woman with a history of chronic atrial fibrillation (AF). The ECG showed a flat baseline with no AF waves and regular, narrow QRS complexes, whereas the previous ECG demonstrated AF. Echocardiography revealed dilation of the right atrium and the tricuspid annulus with severe regurgitation, but mitral regurgitation was mild.
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