AI Article Synopsis
- The treatment of aneurysms faces challenges due to varying shapes and abnormal blood flow analysis, which conventional DSA imaging struggles to capture effectively because of low frame rates.
- High-Speed Angiography (HSA) at 1000 fps offers improved flow detail resolution, aiding clinicians in vascular interventions by clearly differentiating flow features like vortex formations and endoleaks in aneurysm models.
- Through experiments with patient-specific internal carotid artery aneurysm phantoms, simultaneous biplane HSA provided detailed visualizations of flow changes before and after stent deployment, highlighting its potential for enhanced interventional guidance.
Article Abstract
A significant challenge regarding the treatment of aneurysms is the variability in morphology and analysis of abnormal flow. With conventional DSA, low frame rates limit the flow information available to clinicians at the time of the vascular intervention. With 1000 fps High-Speed Angiography (HSA), high frame rates enable flow details to be better resolved for endovascular interventional guidance. The purpose of this work is to demonstrate how 1000 fps biplane-HSA can be used to differentiate flow features, such as vortex formation and endoleaks, amongst patient-specific internal carotid artery aneurysm phantoms pre- and post-endovascular intervention using an in-vitro flow setup. The aneurysm phantoms were attached to a flow loop configured to a carotid waveform, with automated injections of contrast media. Simultaneous Biplane High-Speed Angiographic (SB- HSA) acquisitions were obtained at 1000 fps using two photon-counting detectors with the respective aneurysm and inflow/ outflow vasculature in the FOV. After x-rays were turned on, the detector acquisitions occurred simultaneously, during which iodine contrast was injected at a continuous rate. A pipeline stent was then deployed to divert flow from the aneurysm, and image sequences were once again acquired using the same parameters. Optical Flow, an algorithm that calculates velocity based on spatial-temporal intensity changes between pixels, was used to derive velocity distributions from HSA image sequences. Both the image sequences and velocity distributions indicate detailed changes in flow features amongst the aneurysms before and after deployment of the interventional device. SB-HSA can provide detailed flow analysis, including streamline and velocity changes, which may be beneficial for interventional guidance.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327492 | PMC |
| http://dx.doi.org/10.1117/12.2653622 | DOI Listing |
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