The Genetics of Canine Pulmonary Valve Stenosis.

Vet Clin North Am Small Anim Pract

Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California Davis, UC Davis VMTH, 1 Garrod Drive, Davis, CA 95616, USA.

Published: November 2023

There have been recent advancements in understanding the genetic contribution to pulmonary valve stenosis (PS) in brachycephalic breeds such as the French Bulldog and Bulldog. The associated genes are transcriptions factors involved in cardiac development, which is comparable to the genes that cause PS in humans. However, validation studies and functional follow up is necessary before this information can be used for screening purposes.

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Source
http://dx.doi.org/10.1016/j.cvsm.2023.05.014DOI Listing

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