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A contemporary, multiinstitutional analysis of transcription factor lineage in pituitary adenomas: comparative study of neuroimaging, histopathology, and clinical outcomes.
J Neurosurg
March 2025
1Department of Neurological Surgery, University of Southern California, Keck School of Medicine, Los Angeles, California.
Objective: Pituitary adenomas (PAs) are common lesions that often present with endocrinopathy and/or visual symptoms. Classification of PAs has historically been based on functional status and histopathological staining of anterior pituitary hormones. In 2017, the WHO revised the classification of PAs, establishing cell lineages identified by the transcription factors (TFs) PIT1, TPIT, and SF1.
View Article and Find Full Text PDFEffects of different sources of lactoferrin on cytokine response to SARS-COV-2, respiratory syncytial virus, and rotavirus infection in vitro.
Biochem Cell Biol
March 2025
University of California at Davis, Davis, California, United States;
Lactoferrin (Lf) is a multifunctional iron-binding glycoprotein, involved in a wide range of bioactivities, including immunomodulatory and antiviral activities. Lf in human milk and bovine Lf added to infant formula may provide some protection against viral infections. However, functions of Lfs from different sources may differ due to varying manufacturing processes and posttranslational modifications.
View Article and Find Full Text PDFCharge Dynamics of an Unconventional Three-Dimensional Charge Density Wave in Kagome FeGe.
Phys Rev Lett
February 2025
Institute of Physics, Beijing National Laboratory for Condensed Matter Physics, Chinese Academy of Sciences, P.O. Box 603, Beijing 100190, China.
We report on the charge dynamics of kagome FeGe, an antiferromagnet with a charge density wave (CDW) transition at T_{CDW}≃105 K, using polarized infrared spectroscopy and band structure calculations. We reveal pronounced optical anisotropy along the a and c axis, as well as an unusual response associated with three-dimensional CDW order. Above T_{CDW}, there is a notable transfer of spectral weight (SW) from high to low energies, promoted by the magnetic splitting-induced shift in bands.
View Article and Find Full Text PDFNonorthogonal Eigenvectors, Fluctuation-Dissipation Relations, and Entropy Production.
Phys Rev Lett
February 2025
Jagiellonian University, Institute of Theoretical Physics and Mark Kac Center for Complex Systems Research, Kraków, Poland.
Celebrated fluctuation-dissipation theorem (FDT) linking the response function to time dependent correlations of observables measured in the reference unperturbed state is one of the central results in equilibrium statistical mechanics. In this Letter we discuss an extension of the standard FDT to the case when multidimensional matrix representing transition probabilities is strictly non-normal. This feature dramatically modifies the dynamics, by incorporating the effect of eigenvector nonorthogonality via the associated overlap matrix of Chalker-Mehlig type.
View Article and Find Full Text PDFOrigin of Nonlinear Circular Photocurrent in 2D Semiconductor MoS_{2}.
Phys Rev Lett
February 2025
Institute of Physics, Chinese Academy of Sciences, Beijing National Laboratory for Condensed Matter Physics, Key Laboratory for Nanoscale Physics and Devices, Beijing, 100190, China.
Nonlinear photogalvanic effects in two-dimensional materials, particularly the nonlinear circular photocurrents (NCPs) that belong to the helicity-dependent spin photocurrents, have sparked enormous research interest. Although notable progress has been witnessed, the underling origin of NCPs remains elusive. Here, we present systematic photocurrent characteristics, symmetry analysis and theoretical calculations to uncover the physical origin of NCPs in MoS_{2}, a prototypical 2D semiconductor.
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